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Page 1
Skin γδ T cell inflammatory responses are hardwired in the thymus by oxysterol sensing via GPR183 and calibrated by dietary cholesterol.
Frascoli M, Ferraj E, Miu B, Malin J, Spidale NA, Cowan J, Shissler SC, Brink R, Xu Y, Cyster JG, Bhandoola A, Kang J, Reboldi A. Frascoli M, et al. Among authors: bhandoola a. Immunity. 2023 Mar 14;56(3):562-575.e6. doi: 10.1016/j.immuni.2023.01.025. Epub 2023 Feb 25. Immunity. 2023. PMID: 36842431 Free PMC article.
Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the T cell memory decision.
Abadie K, Clark EC, Valanparambil RM, Ukogu O, Yang W, Daza RM, Ng KKH, Fathima J, Wang AL, Lee J, Nasti TH, Bhandoola A, Nourmohammad A, Ahmed R, Shendure J, Cao J, Kueh HY. Abadie K, et al. Among authors: bhandoola a. Immunity. 2024 Feb 13;57(2):271-286.e13. doi: 10.1016/j.immuni.2023.12.006. Epub 2024 Jan 31. Immunity. 2024. PMID: 38301652 Free article.
Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut.
Das A, Martinez-Ruiz GU, Bouladoux N, Stacy A, Moraly J, Vega-Sendino M, Zhao Y, Lavaert M, Ding Y, Morales-Sanchez A, Harly C, Seedhom MO, Chari R, Awasthi P, Ikeuchi T, Wang Y, Zhu J, Moutsopoulos NM, Chen W, Yewdell JW, Shapiro VS, Ruiz S, Taylor N, Belkaid Y, Bhandoola A. Das A, et al. Among authors: bhandoola a. Immunity. 2024 May 14;57(5):1019-1036.e9. doi: 10.1016/j.immuni.2024.04.001. Epub 2024 Apr 26. Immunity. 2024. PMID: 38677292
Transcription factor TCF-1 regulates the functions, but not the development, of lymphoid tissue inducer subsets in different tissues.
Zheng M, Yao C, Ren G, Mao K, Chung H, Chen X, Hu G, Wang L, Luan X, Fang D, Li D, Zhong C, Lu X, Cannon N, Zhang M, Bhandoola A, Zhao K, O'Shea JJ, Zhu J. Zheng M, et al. Among authors: bhandoola a. Cell Rep. 2023 Aug 29;42(8):112924. doi: 10.1016/j.celrep.2023.112924. Epub 2023 Aug 3. Cell Rep. 2023. PMID: 37540600 Free PMC article.
High-dimensional single-cell analysis of human natural killer cell heterogeneity.
Rebuffet L, Melsen JE, Escalière B, Basurto-Lozada D, Bhandoola A, Björkström NK, Bryceson YT, Castriconi R, Cichocki F, Colonna M, Davis DM, Diefenbach A, Ding Y, Haniffa M, Horowitz A, Lanier LL, Malmberg KJ, Miller JS, Moretta L, Narni-Mancinelli E, O'Neill LAJ, Romagnani C, Ryan DG, Sivori S, Sun D, Vagne C, Vivier E. Rebuffet L, et al. Among authors: bhandoola a. Nat Immunol. 2024 Aug;25(8):1474-1488. doi: 10.1038/s41590-024-01883-0. Epub 2024 Jul 2. Nat Immunol. 2024. PMID: 38956378 Free PMC article.
An epigenetically distinct HSC subset supports thymic reconstitution.
Elias HK, Mitra S, da Silva MB, Rajagopalan A, Gipson B, Lee N, Kousa AI, Ali MAE, Grassman S, Zhang X, DeWolf S, Smith M, Andrlova H, Argyropoulos KV, Sharma R, Fei T, Sun JC, Dunbar CE, Park CY, Leslie CS, Bhandoola A, van den Brink MRM. Elias HK, et al. Among authors: bhandoola a. bioRxiv [Preprint]. 2024 Jun 21:2024.06.06.597775. doi: 10.1101/2024.06.06.597775. bioRxiv. 2024. PMID: 38895335 Free PMC article. Preprint.
Bone marrow plasma cells require P2RX4 to sense extracellular ATP.
Ishikawa M, Hasanali ZS, Zhao Y, Das A, Lavaert M, Roman CJ, Londregan J, Allman D, Bhandoola A. Ishikawa M, et al. Among authors: bhandoola a. Nature. 2024 Feb;626(8001):1102-1107. doi: 10.1038/s41586-024-07047-2. Epub 2024 Feb 14. Nature. 2024. PMID: 38355795 Free PMC article.
Expression of the transcription factor Klf6 by thymic epithelial cells is required for thymus development.
Malin J, Martinez-Ruiz GU, Zhao Y, Shissler SC, Cowan JE, Ding Y, Morales-Sanchez A, Ishikawa M, Lavaert M, Das A, Butcher D, Warner AC, Kallarakal M, Chen J, Kedei N, Kelly M, Brinster LR, Allman D, Bhandoola A. Malin J, et al. Among authors: bhandoola a. Sci Adv. 2023 Nov 17;9(46):eadg8126. doi: 10.1126/sciadv.adg8126. Epub 2023 Nov 15. Sci Adv. 2023. PMID: 37967174 Free PMC article.
137 results