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Page 1
A burden of rare copy number variants in obsessive-compulsive disorder.
Halvorsen MW, de Schipper E, Bäckman J, Strom NI, Hagen K; Nordic OCD and Related Disorders Consortium (NORDiC); Lindblad-Toh K, Karlsson EK, Pedersen NL, Wallert J, Bulik CM, Fundín B, Landén M, Kvale G, Hansen B, Haavik J, Mattheisen M, Rück C, Mataix-Cols D, Crowley JJ. Halvorsen MW, et al. Among authors: backman j. Mol Psychiatry. 2024 Oct 27. doi: 10.1038/s41380-024-02763-7. Online ahead of print. Mol Psychiatry. 2024. PMID: 39463448
Joint testing of rare variant burden scores using non-negative least squares.
Ziyatdinov A, Mbatchou J, Marcketta A, Backman J, Gaynor S, Zou Y, Joseph T, Geraghty B, Herman J, Watanabe K, Ghosh A, Kosmicki J, Locke A; Regeneron Genetics Center; Thornton T, Kang HM, Ferreira M, Baras A, Abecasis G, Marchini J. Ziyatdinov A, et al. Among authors: backman j. Am J Hum Genet. 2024 Oct 3;111(10):2139-2149. doi: 10.1016/j.ajhg.2024.08.021. Am J Hum Genet. 2024. PMID: 39366334 Free PMC article.
Yield of genetic association signals from genomes, exomes and imputation in the UK Biobank.
Gaynor SM, Joseph T, Bai X, Zou Y, Boutkov B, Maxwell EK, Delaneau O, Hofmeister RJ, Krasheninina O, Balasubramanian S, Marcketta A, Backman J; Regeneron Genetics Center; Reid JG, Overton JD, Lotta LA, Marchini J, Salerno WJ, Baras A, Abecasis GR, Thornton TA. Gaynor SM, et al. Among authors: backman j. Nat Genet. 2024 Sep 25. doi: 10.1038/s41588-024-01930-4. Online ahead of print. Nat Genet. 2024. PMID: 39322778
Early change in specific depression symptoms and later outcome in internet-delivered psychotherapy for depression: A cohort study and cross-lagged network analysis.
Johansson F, Flygare O, Bäckman J, Fondberg R, Axelsson E, Forsell E, Cervin M, Kaldo V, Rück C, Wallert J. Johansson F, et al. Among authors: backman j. J Affect Disord. 2024 Sep 16;368:420-428. doi: 10.1016/j.jad.2024.09.092. Online ahead of print. J Affect Disord. 2024. PMID: 39293595 Free article.
NOTCH3 p.Arg1231Cys is markedly enriched in South Asians and associated with stroke.
Rodriguez-Flores JL, Khalid S, Parikshak N, Rasheed A, Ye B, Kapoor M, Backman J, Sepehrband F, Gioia SAD, Gelfman S, De T, Banerjee N, Sharma D, Martinez H, Castaneda S, D'Ambrosio D, Zhang XA, Xun P, Tsai E, Tsai IC; Regeneron Genetics Center; Khan MZ, Jahanzaib M, Mian MR, Liaqat MB, Mahmood K, Salam TU, Hussain M, Iqbal J, Aslam F, Cantor MN, Tzoneva G, Overton J, Marchini J, Reid JG, Baras A, Verweij N, Lotta LA, Coppola G, Karalis K, Economides A, Fazio S, Liedtke W, Danesh J, Kamal A, Frossard P, Coleman T, Shuldiner AR, Saleheen D. Rodriguez-Flores JL, et al. Among authors: backman j. Nat Commun. 2024 Sep 13;15(1):8029. doi: 10.1038/s41467-024-51819-3. Nat Commun. 2024. PMID: 39271666 Free PMC article.
Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone.
Dunn ME, Kithcart A, Kim JH, Ho AJ, Franklin MC, Romero Hernandez A, de Hoon J, Botermans W, Meyer J, Jin X, Zhang D, Torello J, Jasewicz D, Kamat V, Garnova E, Liu N, Rosconi M, Pan H, Karnik S, Burczynski ME, Zheng W, Rafique A, Nielsen JB, De T, Verweij N, Pandit A, Locke A, Chalasani N, Melander O, Schwantes-An TH; Penn Medicine Biobank; Baras A, Lotta LA, Musser BJ, Mastaitis J, Devalaraja-Narashimha KB, Rankin AJ, Huang T, Herman G, Olson W, Murphy AJ, Yancopoulos GD, Olenchock BA, Morton L. Dunn ME, et al. Nature. 2024 Sep;633(8030):654-661. doi: 10.1038/s41586-024-07903-1. Epub 2024 Sep 11. Nature. 2024. PMID: 39261724 Free PMC article. Clinical Trial.
319 results