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l-Type amino acid transporter 1 in hypothalamic neurons in mice maintains energy and bone homeostasis.
Park G, Fukasawa K, Horie T, Masuo Y, Inaba Y, Tatsuno T, Yamada T, Tokumura K, Iwahashi S, Iezaki T, Kaneda K, Kato Y, Ishigaki Y, Mieda M, Tanaka T, Ogawa K, Ochi H, Sato S, Shi YB, Inoue H, Lee H, Hinoi E. Park G, et al. Among authors: iezaki t. JCI Insight. 2023 Apr 10;8(7):e154925. doi: 10.1172/jci.insight.154925. JCI Insight. 2023. PMID: 36862514 Free PMC article.
The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway.
Ozaki K, Yamada T, Horie T, Ishizaki A, Hiraiwa M, Iezaki T, Park G, Fukasawa K, Kamada H, Tokumura K, Motono M, Kaneda K, Ogawa K, Ochi H, Sato S, Kobayashi Y, Shi YB, Taylor PM, Hinoi E. Ozaki K, et al. Among authors: iezaki t. Sci Signal. 2019 Jul 9;12(589):eaaw3921. doi: 10.1126/scisignal.aaw3921. Sci Signal. 2019. PMID: 31289211 Free PMC article.
[Transcription Regulators and Bone Metabolism].
Hinoi E, Iezaki T, Fukasawa K, Kaneda K. Hinoi E, et al. Among authors: iezaki t. Yakugaku Zasshi. 2019;139(1):15-18. doi: 10.1248/yakushi.18-00154-1. Yakugaku Zasshi. 2019. PMID: 30606922 Free article. Review. Japanese.
mTOR regulates skeletogenesis through canonical and noncanonical pathways.
Tokumura K, Iwahashi S, Park G, Ochiai S, Okayama Y, Fusawa H, Fukasawa K, Iezaki T, Hinoi E. Tokumura K, et al. Among authors: iezaki t. Biochem Biophys Res Commun. 2020 Nov 26;533(1):30-35. doi: 10.1016/j.bbrc.2020.09.002. Epub 2020 Sep 8. Biochem Biophys Res Commun. 2020. PMID: 32917361
The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis.
Yamada T, Fukasawa K, Horie T, Kadota T, Lyu J, Tokumura K, Ochiai S, Iwahashi S, Suzuki A, Park G, Ueda R, Yamamoto M, Kitao T, Shirahase H, Ochi H, Sato S, Iezaki T, Hinoi E. Yamada T, et al. Among authors: iezaki t. Stem Cell Reports. 2022 Jul 12;17(7):1576-1588. doi: 10.1016/j.stemcr.2022.06.001. Epub 2022 Jun 30. Stem Cell Reports. 2022. PMID: 35777359 Free PMC article.
Conditional inactivation of the L-type amino acid transporter LAT1 in chondrocytes models idiopathic scoliosis in mice.
Iwahashi S, Lyu J, Tokumura K, Osumi R, Hiraiwa M, Kubo T, Horie T, Demura S, Kawakami N, Saito T, Park G, Fukasawa K, Iezaki T, Suzuki A, Tomizawa A, Ochi H, Hojo H, Ohba S, Hinoi E. Iwahashi S, et al. Among authors: iezaki t. J Cell Physiol. 2022 Nov;237(11):4292-4302. doi: 10.1002/jcp.30883. Epub 2022 Sep 26. J Cell Physiol. 2022. PMID: 36161979
ATF3 controls proliferation of osteoclast precursor and bone remodeling.
Fukasawa K, Park G, Iezaki T, Horie T, Kanayama T, Ozaki K, Onishi Y, Takahata Y, Yoneda Y, Takarada T, Kitajima S, Vacher J, Hinoi E. Fukasawa K, et al. Among authors: iezaki t. Sci Rep. 2016 Aug 2;6:30918. doi: 10.1038/srep30918. Sci Rep. 2016. PMID: 27480204 Free PMC article.
41 results