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In vitro and in vivo effects of zoledronate on senescence and senescence-associated secretory phenotype markers.
Samakkarnthai P, Saul D, Zhang L, Aversa Z, Doolittle ML, Sfeir JG, Kaur J, Atkinson EJ, Edwards JR, Russell RGG, Pignolo RJ, Kirkland JL, Tchkonia T, Niedernhofer LJ, Monroe DG, LeBrasseur NK, Farr JN, Robbins PD, Khosla S. Samakkarnthai P, et al. Among authors: doolittle ml. bioRxiv [Preprint]. 2023 Feb 24:2023.02.23.529777. doi: 10.1101/2023.02.23.529777. bioRxiv. 2023. Update in: Aging (Albany NY). 2023 May 7;15(9):3331-3355. doi: 10.18632/aging.204701 PMID: 36865244 Free PMC article. Updated. Preprint.
Osteocyte Cellular Senescence.
Farr JN, Kaur J, Doolittle ML, Khosla S. Farr JN, et al. Among authors: doolittle ml. Curr Osteoporos Rep. 2020 Oct;18(5):559-567. doi: 10.1007/s11914-020-00619-x. Curr Osteoporos Rep. 2020. PMID: 32794138 Free PMC article. Review.
Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner.
Lagnado A, Leslie J, Ruchaud-Sparagano MH, Victorelli S, Hirsova P, Ogrodnik M, Collins AL, Vizioli MG, Habiballa L, Saretzki G, Evans SA, Salmonowicz H, Hruby A, Geh D, Pavelko KD, Dolan D, Reeves HL, Grellscheid S, Wilson CH, Pandanaboyana S, Doolittle M, von Zglinicki T, Oakley F, Gallage S, Wilson CL, Birch J, Carroll B, Chapman J, Heikenwalder M, Neretti N, Khosla S, Masuda CA, Tchkonia T, Kirkland JL, Jurk D, Mann DA, Passos JF. Lagnado A, et al. EMBO J. 2021 May 3;40(9):e106048. doi: 10.15252/embj.2020106048. Epub 2021 Mar 25. EMBO J. 2021. PMID: 33764576 Free PMC article.
Skeletal Effects of Inducible ERα Deletion in Osteocytes in Adult Mice.
Doolittle ML, Saul D, Kaur J, Rowsey JL, Eckhardt B, Vos S, Grain S, Kroupova K, Ruan M, Weivoda M, Oursler MJ, Farr JN, Monroe DG, Khosla S. Doolittle ML, et al. J Bone Miner Res. 2022 Sep;37(9):1750-1760. doi: 10.1002/jbmr.4644. Epub 2022 Jul 22. J Bone Miner Res. 2022. PMID: 35789113 Free PMC article.
27 results