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Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk.
Forteza MJ, Berg M, Edsfeldt A, Sun J, Baumgartner R, Kareinen I, Casagrande FB, Hedin U, Zhang S, Vuckovic I, Dzeja PP, Polyzos KA, Gisterå A, Trauelsen M, Schwartz TW, Dib L, Herrmann J, Monaco C, Matic L, Gonçalves I, Ketelhuth DFJ. Forteza MJ, et al. Among authors: hedin u. Cardiovasc Res. 2023 Jul 4;119(7):1524-1536. doi: 10.1093/cvr/cvad038. Cardiovasc Res. 2023. PMID: 36866436 Free PMC article.
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.
Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A, Folkersen L, Ueland T, Berge RK, Hansson GK, Biessen EA, Halvorsen B, Bjørås M, Aukrust P. Skarpengland T, et al. Among authors: hedin u. Sci Rep. 2016 Jun 22;6:28337. doi: 10.1038/srep28337. Sci Rep. 2016. PMID: 27328939 Free PMC article.
TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells.
Kim JB, Pjanic M, Nguyen T, Miller CL, Iyer D, Liu B, Wang T, Sazonova O, Carcamo-Orive I, Matic LP, Maegdefessel L, Hedin U, Quertermous T. Kim JB, et al. Among authors: hedin u. PLoS Genet. 2017 May 8;13(5):e1006750. doi: 10.1371/journal.pgen.1006750. eCollection 2017 May. PLoS Genet. 2017. PMID: 28481916 Free PMC article.
Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions.
Jin H, Li DY, Chernogubova E, Sun C, Busch A, Eken SM, Saliba-Gustafsson P, Winter H, Winski G, Raaz U, Schellinger IN, Simon N, Hegenloh R, Matic LP, Jagodic M, Ehrenborg E, Pelisek J, Eckstein HH, Hedin U, Backlund A, Maegdefessel L. Jin H, et al. Among authors: hedin u. Mol Ther. 2018 Apr 4;26(4):1040-1055. doi: 10.1016/j.ymthe.2018.01.011. Epub 2018 Jan 31. Mol Ther. 2018. PMID: 29503197 Free PMC article.
Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques.
Tomas L, Edsfeldt A, Mollet IG, Perisic Matic L, Prehn C, Adamski J, Paulsson-Berne G, Hedin U, Nilsson J, Bengtsson E, Gonçalves I, Björkbacka H. Tomas L, et al. Among authors: hedin u. Eur Heart J. 2018 Jun 21;39(24):2301-2310. doi: 10.1093/eurheartj/ehy124. Eur Heart J. 2018. PMID: 29562241 Free PMC article.
Integrated Human Evaluation of the Lysophosphatidic Acid Pathway as a Novel Therapeutic Target in Atherosclerosis.
Aldi S, Matic LP, Hamm G, van Keulen D, Tempel D, Holmstrøm K, Szwajda A, Nielsen BS, Emilsson V, Ait-Belkacem R, Lengquist M, Paulsson-Berne G, Eriksson P, Lindeman JHN, Gool AJ, Stauber J, Hedin U, Hurt-Camejo E. Aldi S, et al. Among authors: hedin u. Mol Ther Methods Clin Dev. 2018 Jun 27;10:17-28. doi: 10.1016/j.omtm.2018.05.003. eCollection 2018 Sep 21. Mol Ther Methods Clin Dev. 2018. PMID: 30003117 Free PMC article.
246 results