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iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Li X, Maretzky T, Weskamp G, Monette S, Qing X, Issuree PD, Crawford HC, McIlwain DR, Mak TW, Salmon JE, Blobel CP. Li X, et al. Among authors: maretzky t. Proc Natl Acad Sci U S A. 2015 May 12;112(19):6080-5. doi: 10.1073/pnas.1505649112. Epub 2015 Apr 27. Proc Natl Acad Sci U S A. 2015. PMID: 25918388 Free PMC article.
Loss of RHBDF2 results in an early-onset spontaneous murine colitis.
Geesala R, Schanz W, Biggs M, Dixit G, Skurski J, Gurung P, Meyerholz DK, Elliott D, Issuree PD, Maretzky T. Geesala R, et al. Among authors: maretzky t. J Leukoc Biol. 2019 Apr;105(4):767-781. doi: 10.1002/JLB.4A0718-283RR. Epub 2019 Jan 29. J Leukoc Biol. 2019. PMID: 30694569 Free PMC article.
The Role of iRhom2 in Metabolic and Cardiovascular-Related Disorders.
Geesala R, Issuree PD, Maretzky T. Geesala R, et al. Among authors: maretzky t. Front Cardiovasc Med. 2020 Nov 24;7:612808. doi: 10.3389/fcvm.2020.612808. eCollection 2020. Front Cardiovasc Med. 2020. PMID: 33330676 Free PMC article. Review.
49 results