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Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion.
Jeong YJ, Knutsdottir H, Shojaeian F, Lerner MG, Wissler MF, Henriet E, Ng T, Datta S, Navarro-Serer B, Chianchiano P, Kinny-Köster B, Zimmerman JW, Stein-O'Brien G, Gaida MM, Eshleman JR, Lin MT, Fertig EJ, Ewald AJ, Bader JS, Wood LD. Jeong YJ, et al. Among authors: ewald aj. J Clin Invest. 2023 Apr 17;133(8):e162054. doi: 10.1172/JCI162054. J Clin Invest. 2023. PMID: 36881486 Free PMC article.
Between-tumor and within-tumor heterogeneity in invasive potential.
Padmanaban V, Tsehay Y, Cheung KJ, Ewald AJ, Bader JS. Padmanaban V, et al. Among authors: ewald aj. PLoS Comput Biol. 2020 Jan 21;16(1):e1007464. doi: 10.1371/journal.pcbi.1007464. eCollection 2020 Jan. PLoS Comput Biol. 2020. PMID: 31961880 Free PMC article.
Pattern of Invasion in Human Pancreatic Cancer Organoids Is Associated with Loss of SMAD4 and Clinical Outcome.
Huang W, Navarro-Serer B, Jeong YJ, Chianchiano P, Xia L, Luchini C, Veronese N, Dowiak C, Ng T, Trujillo MA, Huang B, Pflüger MJ, Macgregor-Das AM, Lionheart G, Jones D, Fujikura K, Nguyen-Ngoc KV, Neumann NM, Groot VP, Hasanain A, van Oosten AF, Fischer SE, Gallinger S, Singhi AD, Zureikat AH, Brand RE, Gaida MM, Heinrich S, Burkhart RA, He J, Wolfgang CL, Goggins MG, Thompson ED, Roberts NJ, Ewald AJ, Wood LD. Huang W, et al. Among authors: ewald aj. Cancer Res. 2020 Jul 1;80(13):2804-2817. doi: 10.1158/0008-5472.CAN-19-1523. Epub 2020 May 6. Cancer Res. 2020. PMID: 32376602 Free PMC article.
Cancer cells educate natural killer cells to a metastasis-promoting cell state.
Chan IS, Knútsdóttir H, Ramakrishnan G, Padmanaban V, Warrier M, Ramirez JC, Dunworth M, Zhang H, Jaffee EM, Bader JS, Ewald AJ. Chan IS, et al. Among authors: ewald aj. J Cell Biol. 2020 Sep 7;219(9):e202001134. doi: 10.1083/jcb.202001134. J Cell Biol. 2020. PMID: 32645139 Free PMC article.
108 results