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Reduced G protein signaling despite impaired internalization and β-arrestin recruitment in patients carrying a CXCR4Leu317fsX3 mutation causing WHIM syndrome.
Kumar R, Milanesi S, Szpakowska M, Dotta L, Di Silvestre D, Trotta AM, Bello AM, Giacomelli M, Benedito M, Azevedo J, Pereira A, Cortesao E, Vacchini A, Castagna A, Pinelli M, Moratto D, Bonecchi R, Locati M, Scala S, Chevigné A, Borroni EM, Badolato R. Kumar R, et al. Among authors: bonecchi r. JCI Insight. 2023 Mar 8;8(5):e145688. doi: 10.1172/jci.insight.145688. JCI Insight. 2023. PMID: 36883568 Free PMC article.
Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.
Martinez de la Torre Y, Buracchi C, Borroni EM, Dupor J, Bonecchi R, Nebuloni M, Pasqualini F, Doni A, Lauri E, Agostinis C, Bulla R, Cook DN, Haribabu B, Meroni P, Rukavina D, Vago L, Tedesco F, Vecchi A, Lira SA, Locati M, Mantovani A. Martinez de la Torre Y, et al. Among authors: bonecchi r. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2319-24. doi: 10.1073/pnas.0607514104. Epub 2007 Feb 5. Proc Natl Acad Sci U S A. 2007. PMID: 17283337 Free PMC article.
Chemokines as pharmacological targets.
Galliera E, Corsi MM, Bonecchi R, Locati M, Mantovani A. Galliera E, et al. Among authors: bonecchi r. Mini Rev Med Chem. 2008 Jun;8(7):638-46. doi: 10.2174/138955708784567386. Mini Rev Med Chem. 2008. PMID: 18537719 Review.
84 results