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Transcription elongation defects link oncogenic splicing factor mutations to targetable alterations in chromatin landscape.
Boddu PC, Gupta A, Roy R, De La Pena Avalos B, Herrero AO, Neuenkirchen N, Zimmer J, Chandhok N, King D, Nannya Y, Ogawa S, Lin H, Simon M, Dray E, Kupfer G, Verma AK, Neugebauer KM, Pillai MM. Boddu PC, et al. Among authors: dray e. bioRxiv [Preprint]. 2023 Feb 26:2023.02.25.530019. doi: 10.1101/2023.02.25.530019. bioRxiv. 2023. Update in: Mol Cell. 2024 Apr 18;84(8):1475-1495.e18. doi: 10.1016/j.molcel.2024.02.032 PMID: 36891287 Free PMC article. Updated. Preprint.
Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape.
Boddu PC, Gupta AK, Roy R, De La Peña Avalos B, Olazabal-Herrero A, Neuenkirchen N, Zimmer JT, Chandhok NS, King D, Nannya Y, Ogawa S, Lin H, Simon MD, Dray E, Kupfer GM, Verma A, Neugebauer KM, Pillai MM. Boddu PC, et al. Among authors: dray e. Mol Cell. 2024 Apr 18;84(8):1475-1495.e18. doi: 10.1016/j.molcel.2024.02.032. Epub 2024 Mar 22. Mol Cell. 2024. PMID: 38521065
Tumour-intrinsic PDL1 signals regulate the Chk2 DNA damage response in cancer cells and mediate resistance to Chk1 inhibitors.
Murray CE, Kornepati AVR, Ontiveros C, Liao Y, de la Peña Avalos B, Rogers CM, Liu Z, Deng Y, Bai H, Kari S, Padron AS, Boyd JT, Reyes R, Clark CA, Svatek RS, Li R, Hu Y, Wang M, Conejo-Garcia JR, Byers LA, Ramkumar K, Sood AK, Lee JM, Burd CE, Vadlamudi RK, Gupta HB, Zhao W, Dray E, Sung P, Curiel TJ. Murray CE, et al. Among authors: dray e. Mol Cancer. 2024 Oct 30;23(1):242. doi: 10.1186/s12943-024-02147-z. Mol Cancer. 2024. PMID: 39478560 Free PMC article.
Evolved histone tail regulates 53BP1 recruitment at damaged chromatin.
Kelliher JL, Folkerts ML, Shen KV, Song W, Tengler K, Stiefel CM, Lee SO, Dray E, Zhao W, Koss B, Pannunzio NR, Leung JW. Kelliher JL, et al. Among authors: dray e. Nat Commun. 2024 May 31;15(1):4634. doi: 10.1038/s41467-024-49071-w. Nat Commun. 2024. PMID: 38821984 Free PMC article.
63 results