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Page 1
Elevated heart rate and decreased muscle endothelial nitric oxide synthase in early development of insulin resistance.
Blackwood SJ, Tischer D, van de Ven MPF, Pontén M, Edman S, Horwath O, Apró W, Röja J, Ekblom MM, Moberg M, Katz A. Blackwood SJ, et al. Among authors: tischer d. Am J Physiol Endocrinol Metab. 2024 Aug 1;327(2):E172-E182. doi: 10.1152/ajpendo.00148.2024. Epub 2024 Jun 5. Am J Physiol Endocrinol Metab. 2024. PMID: 38836779 Free article.
From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists.
Seep L, Grein S, Splichalova I, Ran D, Mikhael M, Hildebrand S, Lauterbach M, Hiller K, Ribeiro DJS, Sieckmann K, Kardinal R, Huang H, Yu J, Kallabis S, Behrens J, Till A, Peeva V, Strohmeyer A, Bruder J, Blum T, Soriano-Arroquia A, Tischer D, Kuellmer K, Li Y, Beyer M, Gellner AK, Fromme T, Wackerhage H, Klingenspor M, Fenske WK, Scheja L, Meissner F, Schlitzer A, Mass E, Wachten D, Latz E, Pfeifer A, Hasenauer J. Seep L, et al. Among authors: tischer d. Sci Data. 2024 May 22;11(1):524. doi: 10.1038/s41597-024-03349-2. Sci Data. 2024. PMID: 38778016 Free PMC article.
Small-molecule binding and sensing with a designed protein family.
Lee GR, Pellock SJ, Norn C, Tischer D, Dauparas J, Anischenko I, Mercer JAM, Kang A, Bera A, Nguyen H, Goreshnik I, Vafeados D, Roullier N, Han HL, Coventry B, Haddox HK, Liu DR, Yeh AH, Baker D. Lee GR, et al. Among authors: tischer d. bioRxiv [Preprint]. 2023 Nov 2:2023.11.01.565201. doi: 10.1101/2023.11.01.565201. bioRxiv. 2023. PMID: 37961294 Free PMC article. Preprint.
De novo design of small beta barrel proteins.
Kim DE, Jensen DR, Feldman D, Tischer D, Saleem A, Chow CM, Li X, Carter L, Milles L, Nguyen H, Kang A, Bera AK, Peterson FC, Volkman BF, Ovchinnikov S, Baker D. Kim DE, et al. Among authors: tischer d. Proc Natl Acad Sci U S A. 2023 Mar 14;120(11):e2207974120. doi: 10.1073/pnas.2207974120. Epub 2023 Mar 10. Proc Natl Acad Sci U S A. 2023. PMID: 36897987 Free PMC article.
De novo design of luciferases using deep learning.
Yeh AH, Norn C, Kipnis Y, Tischer D, Pellock SJ, Evans D, Ma P, Lee GR, Zhang JZ, Anishchenko I, Coventry B, Cao L, Dauparas J, Halabiya S, DeWitt M, Carter L, Houk KN, Baker D. Yeh AH, et al. Among authors: tischer d. Nature. 2023 Feb;614(7949):774-780. doi: 10.1038/s41586-023-05696-3. Epub 2023 Feb 22. Nature. 2023. PMID: 36813896 Free PMC article.
Robust deep learning-based protein sequence design using ProteinMPNN.
Dauparas J, Anishchenko I, Bennett N, Bai H, Ragotte RJ, Milles LF, Wicky BIM, Courbet A, de Haas RJ, Bethel N, Leung PJY, Huddy TF, Pellock S, Tischer D, Chan F, Koepnick B, Nguyen H, Kang A, Sankaran B, Bera AK, King NP, Baker D. Dauparas J, et al. Among authors: tischer d. Science. 2022 Oct 7;378(6615):49-56. doi: 10.1126/science.add2187. Epub 2022 Sep 15. Science. 2022. PMID: 36108050 Free PMC article.
Scaffolding protein functional sites using deep learning.
Wang J, Lisanza S, Juergens D, Tischer D, Watson JL, Castro KM, Ragotte R, Saragovi A, Milles LF, Baek M, Anishchenko I, Yang W, Hicks DR, Expòsit M, Schlichthaerle T, Chun JH, Dauparas J, Bennett N, Wicky BIM, Muenks A, DiMaio F, Correia B, Ovchinnikov S, Baker D. Wang J, et al. Among authors: tischer d. Science. 2022 Jul 22;377(6604):387-394. doi: 10.1126/science.abn2100. Epub 2022 Jul 21. Science. 2022. PMID: 35862514 Free PMC article.
Protein sequence design by conformational landscape optimization.
Norn C, Wicky BIM, Juergens D, Liu S, Kim D, Tischer D, Koepnick B, Anishchenko I; Foldit Players; Baker D, Ovchinnikov S. Norn C, et al. Among authors: tischer d. Proc Natl Acad Sci U S A. 2021 Mar 16;118(11):e2017228118. doi: 10.1073/pnas.2017228118. Proc Natl Acad Sci U S A. 2021. PMID: 33712545 Free PMC article.
13 results