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Molecular mechanism of biased signaling at the kappa opioid receptor.
El Daibani A, Paggi JM, Kim K, Laloudakis YD, Popov P, Bernhard SM, Krumm BE, Olsen RHJ, Diberto J, Carroll FI, Katritch V, Wünsch B, Dror RO, Che T. El Daibani A, et al. Among authors: wunsch b. Nat Commun. 2023 Mar 11;14(1):1338. doi: 10.1038/s41467-023-37041-7. Nat Commun. 2023. PMID: 36906681 Free PMC article.
Synthesis and pharmacological evaluation of 5-pyrrolidinylquinoxalines as a novel class of peripherally restricted κ-opioid receptor agonists.
Bourgeois C, Werfel E, Galla F, Lehmkuhl K, Torres-Gómez H, Schepmann D, Kögel B, Christoph T, Straßburger W, Englberger W, Soeberdt M, Hüwel S, Galla HJ, Wünsch B. Bourgeois C, et al. Among authors: wunsch b. J Med Chem. 2014 Aug 14;57(15):6845-60. doi: 10.1021/jm500940q. Epub 2014 Aug 5. J Med Chem. 2014. PMID: 25062506
Synthesis of 8-aminomorphans with high KOR affinity.
Jonas H, Aiello D, Schepmann D, Diana P, Wünsch B. Jonas H, et al. Among authors: wunsch b. Eur J Med Chem. 2022 Feb 15;230:114079. doi: 10.1016/j.ejmech.2021.114079. Epub 2022 Jan 5. Eur J Med Chem. 2022. PMID: 35033825
327 results