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Page 1
A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa.
Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Jackow J, Rami A, Hansen C, Guo Z, Gaddam S, Pappalardo A, Li L, Cramer A, Roy KR, Nguyen TM, Tanabe K, McGrath PS, Bruckner A, Bilousova G, Roop D, Bailey I, Tang JY, Christiano A, Steinmetz LM, Wernig M, Oro AE. Neumayer G, et al. Among authors: wernig m. bioRxiv [Preprint]. 2023 Mar 1:2023.02.28.529447. doi: 10.1101/2023.02.28.529447. bioRxiv. 2023. Update in: Nat Commun. 2024 Jul 11;15(1):5834. doi: 10.1038/s41467-024-49400-z PMID: 36909618 Free PMC article. Updated. Preprint.
Augmentation of a neuroprotective myeloid state by hematopoietic cell transplantation.
Mader MM, Napole A, Wu D, Shibuya Y, Scavetti A, Foltz A, Atkins M, Hahn O, Yoo Y, Danziger R, Tan C, Wyss-Coray T, Steinman L, Wernig M. Mader MM, et al. Among authors: wernig m. bioRxiv [Preprint]. 2023 Mar 12:2023.03.10.532123. doi: 10.1101/2023.03.10.532123. bioRxiv. 2023. Update in: Nat Neurosci. 2024 May;27(5):901-912. doi: 10.1038/s41593-024-01609-3 PMID: 36945385 Free PMC article. Updated. Preprint.
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.
Minhas PS, Jones JR, Latif-Hernandez A, Sugiura Y, Durairaj AS, Uenaka T, Wang Q, Mhatre SD, Liu L, Conley T, Ennerfelt H, Jung YJ, Prasad P, Jenkins BC, Goodman R, Newmeyer T, Heard K, Kang A, Wilson EN, Ullian EM, Serrano GE, Beach TG, Rabinowitz JD, Wernig M, Suematsu M, Longo FM, McReynolds MR, Gage FH, Andreasson KI. Minhas PS, et al. Among authors: wernig m. bioRxiv [Preprint]. 2024 Jun 28:2024.06.23.598940. doi: 10.1101/2024.06.23.598940. bioRxiv. 2024. Update in: Science. 2024 Aug 23;385(6711):eabm6131. doi: 10.1126/science.abm6131 PMID: 38979192 Free PMC article. Updated. Preprint.
Proteostasis and lysosomal quality control deficits in Alzheimer's disease neurons.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J. Chou CC, et al. Among authors: wernig m. bioRxiv [Preprint]. 2023 Mar 27:2023.03.27.534444. doi: 10.1101/2023.03.27.534444. bioRxiv. 2023. PMID: 37034684 Free PMC article. Preprint.
A fast and responsive voltage indicator with enhanced sensitivity for unitary synaptic events.
Hao YA, Lee S, Roth RH, Natale S, Gomez L, Taxidis J, O'Neill PS, Villette V, Bradley J, Wang Z, Jiang D, Zhang G, Sheng M, Lu D, Boyden E, Delvendahl I, Golshani P, Wernig M, Feldman DE, Ji N, Ding J, Südhof TC, Clandinin TR, Lin MZ. Hao YA, et al. Among authors: wernig m. Neuron. 2024 Nov 20;112(22):3680-3696.e8. doi: 10.1016/j.neuron.2024.08.019. Epub 2024 Sep 20. Neuron. 2024. PMID: 39305894
RAPIDASH: Tag-free enrichment of ribosome-associated proteins reveals composition dynamics in embryonic tissue, cancer cells, and macrophages.
Susanto TT, Hung V, Levine AG, Chen Y, Kerr CH, Yoo Y, Oses-Prieto JA, Fromm L, Zhang Z, Lantz TC, Fujii K, Wernig M, Burlingame AL, Ruggero D, Barna M. Susanto TT, et al. Among authors: wernig m. Mol Cell. 2024 Sep 19;84(18):3545-3563.e25. doi: 10.1016/j.molcel.2024.08.023. Epub 2024 Sep 10. Mol Cell. 2024. PMID: 39260367
Restoring hippocampal glucose metabolism rescues cognition across Alzheimer's disease pathologies.
Minhas PS, Jones JR, Latif-Hernandez A, Sugiura Y, Durairaj AS, Wang Q, Mhatre SD, Uenaka T, Crapser J, Conley T, Ennerfelt H, Jung YJ, Liu L, Prasad P, Jenkins BC, Ay YA, Matrongolo M, Goodman R, Newmeyer T, Heard K, Kang A, Wilson EN, Yang T, Ullian EM, Serrano GE, Beach TG, Wernig M, Rabinowitz JD, Suematsu M, Longo FM, McReynolds MR, Gage FH, Andreasson KI. Minhas PS, et al. Among authors: wernig m. Science. 2024 Aug 23;385(6711):eabm6131. doi: 10.1126/science.abm6131. Epub 2024 Aug 23. Science. 2024. PMID: 39172838
A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa.
Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Mader MM, Gebeyehu G, Jaouni TM, Jacków-Malinowska J, Rami A, Hansen C, Guo Z, Gaddam S, Tate KM, Pappalardo A, Li L, Chow GM, Roy KR, Nguyen TM, Tanabe K, McGrath PS, Cramer A, Bruckner A, Bilousova G, Roop D, Tang JY, Christiano A, Steinmetz LM, Wernig M, Oro AE. Neumayer G, et al. Among authors: wernig m. Nat Commun. 2024 Jul 11;15(1):5834. doi: 10.1038/s41467-024-49400-z. Nat Commun. 2024. PMID: 38992003 Free PMC article.
Human tNeurons reveal aging-linked proteostasis deficits driving Alzheimer's phenotypes.
Chou CC, Vest R, Prado MA, Wilson-Grady J, Paulo JA, Shibuya Y, Moran-Losada P, Lee TT, Luo J, Gygi SP, Kelly JW, Finley D, Wernig M, Wyss-Coray T, Frydman J. Chou CC, et al. Among authors: wernig m. Res Sq [Preprint]. 2024 May 30:rs.3.rs-4407236. doi: 10.21203/rs.3.rs-4407236/v1. Res Sq. 2024. PMID: 38853828 Free PMC article. Preprint.
147 results