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Gastrin upregulates the prosurvival factor secretory clusterin in adenocarcinoma cells and in oxyntic mucosa of hypergastrinemic rats.
Fjeldbo CS, Bakke I, Erlandsen SE, Holmseth J, Lægreid A, Sandvik AK, Thommesen L, Bruland T. Fjeldbo CS, et al. Among authors: bruland t. Am J Physiol Gastrointest Liver Physiol. 2012 Jan 1;302(1):G21-33. doi: 10.1152/ajpgi.00197.2011. Epub 2011 Oct 13. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 21995960 Free article.
The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival.
Vange P, Bruland T, Doseth B, Fossmark R, Sousa MML, Beisvag V, Sørdal Ø, Qvigstad G, Waldum HL, Sandvik AK, Bakke I. Vange P, et al. Among authors: bruland t. PLoS One. 2017 Sep 13;12(9):e0184514. doi: 10.1371/journal.pone.0184514. eCollection 2017. PLoS One. 2017. PMID: 28902909 Free PMC article.
39 results