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Infection with chikungunya virus confers heterotypic cross-neutralizing antibodies and memory B-cells against other arthritogenic alphaviruses predominantly through the B domain of the E2 glycoprotein.
Powers JM, Lyski ZL, Weber WC, Denton M, Streblow MM, Mayo AT, Haese NN, Nix CD, Rodríguez-Santiago R, Alvarado LI, Rivera-Amill V, Messer WB, Streblow DN. Powers JM, et al. Among authors: streblow mm. PLoS Negl Trop Dis. 2023 Mar 13;17(3):e0011154. doi: 10.1371/journal.pntd.0011154. eCollection 2023 Mar. PLoS Negl Trop Dis. 2023. PMID: 36913428 Free PMC article.
Mayaro virus pathogenesis and immunity in rhesus macaques.
Weber WC, Labriola CS, Kreklywich CN, Ray K, Haese NN, Andoh TF, Denton M, Medica S, Streblow MM, Smith PP, Mizuno N, Frias N, Fisher MB, Barber-Axthelm AM, Chun K, Uttke S, Whitcomb D, DeFilippis V, Rakshe S, Fei SS, Axthelm MK, Smedley JV, Streblow DN. Weber WC, et al. Among authors: streblow mm. PLoS Negl Trop Dis. 2023 Nov 20;17(11):e0011742. doi: 10.1371/journal.pntd.0011742. eCollection 2023 Nov. PLoS Negl Trop Dis. 2023. PMID: 37983245 Free PMC article.
Nonreciprocity in CHIKV and MAYV Vaccine-Elicited Protection.
Weber WC, Andoh TF, Kreklywich CN, Streblow ZJ, Denton M, Streblow MM, Powers JM, Sulgey G, Medica S, Dmitriev I, Curiel DT, Haese NN, Streblow DN. Weber WC, et al. Among authors: streblow mm. Vaccines (Basel). 2024 Aug 27;12(9):970. doi: 10.3390/vaccines12090970. Vaccines (Basel). 2024. PMID: 39340002 Free PMC article.
The Approved Live-Attenuated Chikungunya Virus Vaccine (IXCHIQ®) Elicits Cross-Neutralizing Antibody Breadth Extending to Multiple Arthritogenic Alphaviruses Similar to the Antibody Breadth Following Natural Infection.
Weber WC, Streblow ZJ, Kreklywich CN, Denton M, Sulgey G, Streblow MM, Marcano D, Flores PN, Rodriguez-Santiago RM, Alvarado LI, Rivera-Amill V, Messer WB, Hochreiter R, Kosulin K, Dubischar K, Buerger V, Streblow DN. Weber WC, et al. Among authors: streblow mm. Vaccines (Basel). 2024 Aug 7;12(8):893. doi: 10.3390/vaccines12080893. Vaccines (Basel). 2024. PMID: 39204019 Free PMC article.