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C2230, a preferential use- and state-dependent CaV2.2 channel blocker, mitigates pain behaviors across multiple pain models.
Tang C, Gomez K, Chen Y, Allen HN, Hestehave S, Rodríguez-Palma EJ, Loya-Lopez S, Calderon-Rivera A, Duran P, Nelson TS, Kanumuri SRR, Shah B, Panigrahi NR, Perez-Miller S, Schackmuth MK, Ruparel S, Patwardhan A, Price TJ, Arora PS, Sharma RK, Sharma A, Yu J, Korczeniewska OA, Khanna R. Tang C, et al. Among authors: khanna r. J Clin Invest. 2024 Dec 10:e177429. doi: 10.1172/JCI177429. Online ahead of print. J Clin Invest. 2024. PMID: 39656529 Free article.
Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain.
Calderon-Rivera A, Gomez K, Loya-López S, Wijeratne EMK, Stratton H, Tang C, Duran P, Masterson K, Alsbiei O, Gunatilaka AAL, Khanna R. Calderon-Rivera A, et al. Among authors: khanna r. Neurobiol Pain. 2023 Jan 14;13:100116. doi: 10.1016/j.ynpai.2023.100116. eCollection 2023 Jan-Jul. Neurobiol Pain. 2023. PMID: 36687466 Free PMC article.
NEUROPILIN-1 INHIBITION SUPPRESSES NERVE-GROWTH FACTOR SIGNALING AND NOCICEPTION IN PAIN MODELS.
Peach CJ, Tonello R, Damo E, Gomez K, Calderon-Rivera A, Bruni R, Bansia H, Maile L, Manu AM, Hahn H, Thomsen AR, Schmidt BL, Davidson S, des Georges A, Khanna R, Bunnett NW. Peach CJ, et al. Among authors: khanna r. J Clin Invest. 2024 Nov 26:e183873. doi: 10.1172/JCI183873. Online ahead of print. J Clin Invest. 2024. PMID: 39589827 Free article.
2,141 results