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Multimeric nanobodies from camelid engineered mice and llamas potently neutralize SARS-CoV-2 variants.
Xu J, Xu K, Jung S, Conte A, Lieberman J, Muecksch F, Cetrulo Lorenzi JC, Park S, Wang Z, Tessarollo L, Bylund T, Chuang GY, Olia AS, Stephens T, Teng IT, Tsybovsky Y, Zhou T, Hatziioannou T, Bieniasz PD, Nussenzweig MC, Kwong PD, Casellas R. Xu J, et al. Among authors: tsybovsky y. bioRxiv [Preprint]. 2021 Mar 4:2021.03.04.433768. doi: 10.1101/2021.03.04.433768. bioRxiv. 2021. Update in: Nature. 2021 Jul;595(7866):278-282. doi: 10.1038/s41586-021-03676-z PMID: 33688659 Free PMC article. Updated. Preprint.
Extremely potent monoclonal antibodies neutralize Omicron and other SARS-CoV-2 variants.
Chen Z, Zhang P, Matsuoka Y, Tsybovsky Y, West K, Santos C, Boyd LF, Nguyen H, Pomerenke A, Stephens T, Olia AS, De Giorgi V, Holbrook MR, Gross R, Postnikova E, Garza NL, Johnson RF, Margulies DH, Kwong PD, Alter HJ, Buchholz UJ, Lusso P, Farci P. Chen Z, et al. Among authors: tsybovsky y. medRxiv [Preprint]. 2022 Jan 13:2022.01.12.22269023. doi: 10.1101/2022.01.12.22269023. medRxiv. 2022. Update in: Cell Rep. 2022 Nov 1;41(5):111528. doi: 10.1016/j.celrep.2022.111528 PMID: 35043120 Free PMC article. Updated. Preprint.
Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains.
Zhou T, Tsybovsky Y, Olia AS, Gorman J, Rapp MA, Cerutti G, Chuang GY, Katsamba PS, Nazzari A, Sampson JM, Schon A, Wang PD, Bimela J, Shi W, Teng IT, Zhang B, Boyington JC, Sastry M, Stephens T, Stuckey J, Wang S, Friesner RA, Ho DD, Mascola JR, Shapiro L, Kwong PD. Zhou T, et al. Among authors: tsybovsky y. bioRxiv [Preprint]. 2020 Jul 31:2020.07.04.187989. doi: 10.1101/2020.07.04.187989. bioRxiv. 2020. Update in: Cell Host Microbe. 2020 Dec 9;28(6):867-879.e5. doi: 10.1016/j.chom.2020.11.004 PMID: 32637958 Free PMC article. Updated. Preprint.
131 results