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Page 1
Selective Neuronal Knockout of STAT3 Function Inhibits Epilepsy Progression, Improves Cognition, and Restores Dysregulated Gene Networks in a Temporal Lobe Epilepsy Model.
Tipton AE, Cruz Del Angel Y, Hixson K, Carlsen J, Strode D, Busquet N, Mesches MH, Gonzalez MI, Napoli E, Russek SJ, Brooks-Kayal AR. Tipton AE, et al. Among authors: russek sj. Ann Neurol. 2023 Jul;94(1):106-122. doi: 10.1002/ana.26644. Epub 2023 Apr 7. Ann Neurol. 2023. PMID: 36935347 Free PMC article.
The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
Popik P, Kostakis E, Krawczyk M, Nowak G, Szewczyk B, Krieter P, Chen Z, Russek SJ, Gibbs TT, Farb DH, Skolnick P, Lippa AS, Basile AS. Popik P, et al. Among authors: russek sj. J Pharmacol Exp Ther. 2006 Dec;319(3):1244-52. doi: 10.1124/jpet.106.107201. Epub 2006 Sep 13. J Pharmacol Exp Ther. 2006. PMID: 16971504
Selective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator.
Lippa A, Czobor P, Stark J, Beer B, Kostakis E, Gravielle M, Bandyopadhyay S, Russek SJ, Gibbs TT, Farb DH, Skolnick P. Lippa A, et al. Among authors: russek sj. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7380-5. doi: 10.1073/pnas.0502579102. Epub 2005 May 3. Proc Natl Acad Sci U S A. 2005. PMID: 15870187 Free PMC article. Clinical Trial.
56 results