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Extrahelical Binding Site for a 1H-Imidazo[4,5-c]quinolin-4-amine A3 Adenosine Receptor Positive Allosteric Modulator on Helix 8 and Distal Portions of Transmembrane Domains 1 and 7.
Fisher CL, Pavan M, Salmaso V, Keyes RF, Wan TC, Pradhan B, Gao ZG, Smith BC, Jacobson KA, Auchampach JA. Fisher CL, et al. Among authors: keyes rf. Mol Pharmacol. 2024 Feb 15;105(3):213-223. doi: 10.1124/molpharm.123.000784. Mol Pharmacol. 2024. PMID: 38182432 Free PMC article.
The TRIM33 Bromodomain Recognizes Histone Lysine Lactylation.
Nuñez R, Sidlowski PFW, Steen EA, Wynia-Smith SL, Sprague DJ, Keyes RF, Smith BC. Nuñez R, et al. Among authors: keyes rf. ACS Chem Biol. 2024 Dec 20;19(12):2418-2428. doi: 10.1021/acschembio.4c00248. Epub 2024 Nov 18. ACS Chem Biol. 2024. PMID: 39556662
Characterization of Dual-Acting A3 Adenosine Receptor Positive Allosteric Modulators That Preferentially Enhance Adenosine-Induced Gαi3 and GαoA Isoprotein Activation.
Fisher CL, Fallot LB, Wan TC, Keyes RF, Suresh RR, Rothwell AC, Gao ZG, McCorvy JD, Smith BC, Jacobson KA, Auchampach JA. Fisher CL, et al. Among authors: keyes rf. ACS Pharmacol Transl Sci. 2022 Jul 15;5(8):625-641. doi: 10.1021/acsptsci.2c00076. eCollection 2022 Aug 12. ACS Pharmacol Transl Sci. 2022. PMID: 35983277 Free PMC article.
21 results