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A comparative gene expression matrix in Apoe-deficient mice identifies unique and atherosclerotic disease stage-specific gene regulation patterns in monocytes and macrophages.
Härdtner C, Kumar A, Ehlert CA, Vico TA, Starz C, von Ehr A, Krebs K, Dufner B, Hoppe N, Stachon P, Heidt T, Wolf D, von Zur Mühlen C, Grüning B, Robbins CS, Maegdefessel L, Westermann D, Dederichs TS, Hilgendorf I. Härdtner C, et al. Among authors: krebs k. Atherosclerosis. 2023 Apr;371:1-13. doi: 10.1016/j.atherosclerosis.2023.03.006. Epub 2023 Mar 15. Atherosclerosis. 2023. PMID: 36940535 Free article.
Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering.
Härdtner C, Kornemann J, Krebs K, Ehlert CA, Jander A, Zou J, Starz C, Rauterberg S, Sharipova D, Dufner B, Hoppe N, Dederichs TS, Willecke F, Stachon P, Heidt T, Wolf D, von Zur Mühlen C, Madl J, Kohl P, Kaeser R, Boettler T, Pieterman EJ, Princen HMG, Ho-Tin-Noé B, Swirski FK, Robbins CS, Bode C, Zirlik A, Hilgendorf I. Härdtner C, et al. Among authors: krebs k. Basic Res Cardiol. 2020 Dec 9;115(6):78. doi: 10.1007/s00395-020-00838-4. Basic Res Cardiol. 2020. PMID: 33296022 Free PMC article.
Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe-/- mice.
Leipner J, Dederichs TS, von Ehr A, Rauterberg S, Ehlert C, Merz J, Dufner B, Hoppe N, Krebs K, Heidt T, von Zur Muehlen C, Stachon P, Ley K, Wolf D, Zirlik A, Bode C, Hilgendorf I, Härdtner C. Leipner J, et al. Among authors: krebs k. Mol Metab. 2021 Nov;53:101250. doi: 10.1016/j.molmet.2021.101250. Epub 2021 May 12. Mol Metab. 2021. PMID: 33991749 Free PMC article.
Elevated platelet-leukocyte complexes are associated with, but dispensable for myocardial ischemia-reperfusion injury.
Starz C, Härdtner C, Mauler M, Dufner B, Hoppe N, Krebs K, Ehlert CA, Merz J, Heidt T, Stachon P, Wolf D, Bode C, von Zur Muehlen C, Rottbauer W, Gawaz M, Duerschmied D, Leuschner F, Borst O, Westermann D, Hilgendorf I. Starz C, et al. Among authors: krebs k. Basic Res Cardiol. 2022 Nov 16;117(1):61. doi: 10.1007/s00395-022-00970-3. Basic Res Cardiol. 2022. PMID: 36383299 Free PMC article.
Genomics yields biological and phenotypic insights into bipolar disorder.
O'Connell KS, Koromina M, van der Veen T, Boltz T, David FS, Yang JMK, Lin KH, Wang X, Coleman JRI, Mitchell BL, McGrouther CC, Rangan AV, Lind PA, Koch E, Harder A, Parker N, Bendl J, Adorjan K, Agerbo E, Albani D, Alemany S, Alliey-Rodriguez N, Als TD, Andlauer TFM, Antoniou A, Ask H, Bass N, Bauer M, Beins EC, Bigdeli TB, Pedersen CB, Boks MP, Børte S, Bosch R, Brum M, Brumpton BM, Brunkhorst-Kanaan N, Budde M, Bybjerg-Grauholm J, Byerley W, Cabana-Domínguez J, Cairns MJ, Carpiniello B, Casas M, Cervantes P, Chatzinakos C, Chen HC, Clarence T, Clarke TK, Claus I, Coombes B, Corfield EC, Cruceanu C, Cuellar-Barboza A, Czerski PM, Dafnas K, Dale AM, Dalkner N, Degenhardt F, DePaulo JR, Djurovic S, Drange OK, Escott-Price V, Fanous AH, Fellendorf FT, Ferrier IN, Forty L, Frank J, Frei O, Freimer NB, Fullard JF, Garnham J, Gizer IR, Gordon SD, Gordon-Smith K, Greenwood TA, Grove J, Guzman-Parra J, Ha TH, Hahn T, Haraldsson M, Hautzinger M, Havdahl A, Heilbronner U, Hellgren D, Herms S, Hickie IB, Hoffmann P, Holmans PA, Huang MC, Ikeda M, Jamain S, Johnson JS, Jonsson L, Kalman JL, Kamatani Y, Kennedy JL, Kim E, Kim J, Kittel-Schneider S, Knowles JA, Kogevinas M, Kranz TM, Krebs… See abstract for full author list ➔ O'Connell KS, et al. Among authors: krebs k. Nature. 2025 Jan 22. doi: 10.1038/s41586-024-08468-9. Online ahead of print. Nature. 2025. PMID: 39843750
Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies.
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Electronic address: [email protected]; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Electronic address: [email protected], et al. Cell. 2025 Jan 14:S0092-8674(24)01415-6. doi: 10.1016/j.cell.2024.12.002. Online ahead of print. Cell. 2025. PMID: 39814019 Free article.
Genome-wide meta-analyses of non-response to antidepressants identify novel loci and potential drugs.
Koch E, Jürgenson T, Einarsson G, Mitchell B, Harder A, García-Marín LM, Krebs K, Lin Y, Shadrin A, Xiong Y, Frei O, Lu Y, Hägg S, Renteria M, Medland S, Wray N, Martin N, Hübel C, Breen G, Thorgeirsson T, Stefansson H, Stefansson K, Lehto K, Milani L, Andreassen O, O Connell K. Koch E, et al. Among authors: krebs k. Res Sq [Preprint]. 2024 Dec 23:rs.3.rs-5418279. doi: 10.21203/rs.3.rs-5418279/v1. Res Sq. 2024. PMID: 39764137 Free PMC article. Preprint.
Innovative fixed bed bioreactor platform: Enabling linearly scalable adherent cell biomanufacturing with real-time biomass prediction from nutrient consumption.
Goral VN, Hong Y, Scibek JJ, Sun Y, Romeo LE, Rao A, Manning D, Zhou Y, Schultes JA, Tjong V, Pikula D, Krebs KA, Ferrie AM, Kramel S, Weber JL, Upton TM, Fang Y, Melkoumian Z. Goral VN, et al. Among authors: krebs ka. Biotechnol J. 2024 Aug;19(8):e2300635. doi: 10.1002/biot.202300635. Biotechnol J. 2024. PMID: 39167554
Genome-wide meta-analyses of non-response to antidepressants identify novel loci and potential drugs.
Koch E, Jurgenson T, Einarsson G, Mitchell B, Harder A, Garcia-Marin LM, Krebs K, Lin Y, Xiong Y, Research Team EB, Lu Y, Hagg S, Renteria ME, Medland SE, Wray NR, Martin NG, Huebel C, Breen G, Thorgeirsson T, Stefansson H, Stefansson K, Milani L, Andreassen OA, O'Connell KS. Koch E, et al. Among authors: krebs k. medRxiv [Preprint]. 2024 Jul 15:2024.07.13.24310361. doi: 10.1101/2024.07.13.24310361. medRxiv. 2024. PMID: 39072048 Free PMC article. Preprint.
159 results