Wu X - Search Results

1

Design, synthesis, and biological evaluation of diaryl heterocyclic derivatives targeting tubulin polymerization with potent anticancer activities.

Li G, Wu JQ, Cai X, Guan W, Zeng Z, Ou Y, Wu X, Li J, Fang X, Liu J, Zhang Y, Wang H, Yin C, Yao H. Li G, et al. Among authors: wu x, wu jq. Eur J Med Chem. 2023 Apr 5;252:115284. doi: 10.1016/j.ejmech.2023.115284. Epub 2023 Mar 16. Eur J Med Chem. 2023. PMID: 36940610

2

Design, synthesis, anti-tumor activity, and molecular modeling of quinazoline and pyrido[2,3-d]pyrimidine derivatives targeting epidermal growth factor receptor.

Hou J, Wan S, Wang G, Zhang T, Li Z, Tian Y, Yu Y, Wu X, Zhang J. Hou J, et al. Among authors: wu x. Eur J Med Chem. 2016 Aug 8;118:276-89. doi: 10.1016/j.ejmech.2016.04.026. Epub 2016 Apr 20. Eur J Med Chem. 2016. PMID: 27132165

3

Design, synthesis, biological evaluation and molecular modeling of novel 2-amino-4-(1-phenylethoxy) pyridine derivatives as potential ROS1 inhibitors.

Tian Y, Zhang T, Long L, Li Z, Wan S, Wang G, Yu Y, Hou J, Wu X, Zhang J. Tian Y, et al. Among authors: wu x. Eur J Med Chem. 2018 Jan 1;143:182-199. doi: 10.1016/j.ejmech.2017.11.002. Epub 2017 Nov 3. Eur J Med Chem. 2018. PMID: 29174814

4

Design, synthesis, biological evaluation and molecular modeling of novel 1H-pyrazolo[3,4-d]pyrimidine derivatives as BRAF^V600E and VEGFR-2 dual inhibitors.

Wang Y, Wan S, Li Z, Fu Y, Wang G, Zhang J, Wu X. Wang Y, et al. Among authors: wu x. Eur J Med Chem. 2018 Jul 15;155:210-228. doi: 10.1016/j.ejmech.2018.05.054. Epub 2018 Jun 2. Eur J Med Chem. 2018. PMID: 29886324

5

Design, synthesis and biological evaluations of 2-amino-4-(1-piperidine) pyridine derivatives as novel anti crizotinib-resistant ALK/ROS1 dual inhibitors.

Liu S, Jiang Y, Yan R, Li Z, Wan S, Zhang T, Wu X, Hou J, Zhu Z, Tian Y, Zhang J. Liu S, et al. Among authors: wu x. Eur J Med Chem. 2019 Oct 1;179:358-375. doi: 10.1016/j.ejmech.2019.06.043. Epub 2019 Jun 25. Eur J Med Chem. 2019. PMID: 31260890

6

Design, synthesis and biological evaluation of 2-amino-4-(1,2,4-triazol)pyridine derivatives as potent EGFR inhibitors to overcome TKI-resistance.

Yang H, Yan R, Jiang Y, Yang Z, Zhang X, Zhou M, Wu X, Zhang T, Zhang J. Yang H, et al. Among authors: wu x. Eur J Med Chem. 2020 Feb 1;187:111966. doi: 10.1016/j.ejmech.2019.111966. Epub 2019 Dec 14. Eur J Med Chem. 2020. PMID: 31869655 Review.

7

Design and synthesis of proteolysis targeting chimeras (PROTACs) as an EGFR degrader based on CO-1686.

Li Q, Guo Q, Wang S, Wan S, Li Z, Zhang J, Wu X. Li Q, et al. Among authors: wu x. Eur J Med Chem. 2022 Aug 5;238:114455. doi: 10.1016/j.ejmech.2022.114455. Epub 2022 May 12. Eur J Med Chem. 2022. PMID: 35594654

8

Anti-proliferative activity and structure-activity relationship of honokiol derivatives.

Lin D, Yan Z, Chen A, Ye J, Hu A, Liu J, Peng J, Wu X. Lin D, et al. Among authors: wu x. Bioorg Med Chem. 2019 Aug 15;27(16):3729-3734. doi: 10.1016/j.bmc.2019.06.042. Epub 2019 Jun 27. Bioorg Med Chem. 2019. PMID: 31278004

9

Identification of imidazo[4,5-c]pyridin-2-one derivatives as novel Src family kinase inhibitors against glioblastoma.

Zhang L, Yang Z, Sang H, Jiang Y, Zhou M, Huang C, Huang C, Wu X, Zhang T, Zhang X, Wan S, Zhang J. Zhang L, et al. Among authors: wu x. J Enzyme Inhib Med Chem. 2021 Dec;36(1):1541-1552. doi: 10.1080/14756366.2021.1948542. J Enzyme Inhib Med Chem. 2021. PMID: 34238111 Free PMC article.

10

Discovery of novel Macrocyclic small molecules Based on 2-Amino-4-thiazolylpyridineas selective EGFR inhibitors with high Blood-Brain barrier penetration for the treatment of glioblastoma.

Wu G, Zhou M, Guo F, Lin Y, Chen Y, Kong Y, Xiao J, Wan S, Li Z, Wu X, Zhang T, Zhang J. Wu G, et al. Among authors: wu x. Bioorg Chem. 2024 Dec;153:107905. doi: 10.1016/j.bioorg.2024.107905. Epub 2024 Oct 23. Bioorg Chem. 2024. PMID: 39476599

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

59,230 results

Search Page

Filters