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Efficacy and Safety of Early Administration of 4-Factor Prothrombin Complex Concentrate in Patients With Trauma at Risk of Massive Transfusion: The PROCOAG Randomized Clinical Trial.
Bouzat P, Charbit J, Abback PS, Huet-Garrigue D, Delhaye N, Leone M, Marcotte G, David JS, Levrat A, Asehnoune K, Pottecher J, Duranteau J, Courvalin E, Adolle A, Sourd D, Bosson JL, Riou B, Gauss T, Payen JF; PROCOAG Study Group. Bouzat P, et al. Among authors: courvalin e. JAMA. 2023 Apr 25;329(16):1367-1375. doi: 10.1001/jama.2023.4080. JAMA. 2023. PMID: 36942533 Free PMC article. Clinical Trial.