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Disuse-induced muscle fibrosis, cellular senescence, and senescence-associated secretory phenotype in older adults are alleviated during re-ambulation with metformin pre-treatment.
Petrocelli JJ, McKenzie AI, de Hart NMMP, Reidy PT, Mahmassani ZS, Keeble AR, Kaput KL, Wahl MP, Rondina MT, Marcus RL, Welt CK, Holland WL, Funai K, Fry CS, Drummond MJ. Petrocelli JJ, et al. Among authors: funai k. Aging Cell. 2023 Nov;22(11):e13936. doi: 10.1111/acel.13936. Epub 2023 Jul 24. Aging Cell. 2023. PMID: 37486024 Free PMC article. Clinical Trial.
SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation.
Szulik MW, Valdez S, Walsh M, Davis K, Bia R, Horiuchi E, O'Very S, Laxman AK, Sandaklie-Nicolova L, Eberhardt DR, Durrant JR, Sheikh H, Hickenlooper S, Creed M, Brady C, Miller M, Wang L, Garcia-Llana J, Tracy C, Drakos SG, Funai K, Chaudhuri D, Boudina S, Franklin S. Szulik MW, et al. Among authors: funai k. Basic Res Cardiol. 2023 May 22;118(1):20. doi: 10.1007/s00395-023-00991-6. Basic Res Cardiol. 2023. PMID: 37212935 Free PMC article.
Assessment of Bioenergetics in BAT Mitochondria.
Peterlin AD, Johnson JM, Funai K. Peterlin AD, et al. Among authors: funai k. Methods Mol Biol. 2023;2662:67-75. doi: 10.1007/978-1-0716-3167-6_6. Methods Mol Biol. 2023. PMID: 37076671
Cardiac gene therapy treats diabetic cardiomyopathy and lowers blood glucose.
Li J, Richmond B, Cluntun AA, Bia R, Walsh MA, Shaw K, Symons JD, Franklin S, Rutter J, Funai K, Shaw RM, Hong T. Li J, et al. Among authors: funai k. JCI Insight. 2023 Sep 22;8(18):e166713. doi: 10.1172/jci.insight.166713. JCI Insight. 2023. PMID: 37639557 Free PMC article.
225 results