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A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription.
Frischauf I, Zayats V, Deix M, Hochreiter A, Jardin I, Muik M, Lackner B, Svobodová B, Pammer T, Litviňuková M, Sridhar AA, Derler I, Bogeski I, Romanin C, Ettrich RH, Schindl R. Frischauf I, et al. Among authors: jardin i. Sci Signal. 2015 Dec 22;8(408):ra131. doi: 10.1126/scisignal.aab1901. Sci Signal. 2015. PMID: 26696631 Free PMC article.
Cholesterol modulates Orai1 channel function.
Derler I, Jardin I, Stathopulos PB, Muik M, Fahrner M, Zayats V, Pandey SK, Poteser M, Lackner B, Absolonova M, Schindl R, Groschner K, Ettrich R, Ikura M, Romanin C. Derler I, et al. Among authors: jardin i. Sci Signal. 2016 Jan 26;9(412):ra10. doi: 10.1126/scisignal.aad7808. Sci Signal. 2016. PMID: 26814231 Free PMC article.
95 results