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Immunotherapeutic approach to reduce senescent cells and alleviate senescence-associated secretory phenotype in mice.
Shrestha N, Chaturvedi P, Zhu X, Dee MJ, George V, Janney C, Egan JO, Liu B, Foster M, Marsala L, Wong P, Cubitt CC, Foltz JA, Tran J, Schappe T, Hsiao K, Leclerc GM, You L, Echeverri C, Spanoudis C, Carvalho A, Kanakaraj L, Gilkes C, Encalada N, Kong L, Wang M, Fang B, Wang Z, Jiao JA, Muniz GJ, Jeng EK, Valdivieso N, Li L, Deth R, Berrien-Elliott MM, Fehniger TA, Rhode PR, Wong HC. Shrestha N, et al. Among authors: kong l. Aging Cell. 2023 May;22(5):e13806. doi: 10.1111/acel.13806. Epub 2023 Mar 26. Aging Cell. 2023. PMID: 36967480 Free PMC article.
Targeting activity of a TCR/IL-2 fusion protein against established tumors.
Wen J, Zhu X, Liu B, You L, Kong L, Lee HI, Han KP, Wong JL, Rhode PR, Wong HC. Wen J, et al. Among authors: kong l. Cancer Immunol Immunother. 2008 Dec;57(12):1781-94. doi: 10.1007/s00262-008-0504-7. Epub 2008 Mar 28. Cancer Immunol Immunother. 2008. PMID: 18369620 Free PMC article.
Efficacy and mechanism-of-action of a novel superagonist interleukin-15: interleukin-15 receptor αSu/Fc fusion complex in syngeneic murine models of multiple myeloma.
Xu W, Jones M, Liu B, Zhu X, Johnson CB, Edwards AC, Kong L, Jeng EK, Han K, Marcus WD, Rubinstein MP, Rhode PR, Wong HC. Xu W, et al. Among authors: kong l. Cancer Res. 2013 May 15;73(10):3075-86. doi: 10.1158/0008-5472.CAN-12-2357. Epub 2013 May 3. Cancer Res. 2013. PMID: 23644531 Free PMC article.
The IL-15-Based ALT-803 Complex Enhances FcγRIIIa-Triggered NK Cell Responses and In Vivo Clearance of B Cell Lymphomas.
Rosario M, Liu B, Kong L, Collins LI, Schneider SE, Chen X, Han K, Jeng EK, Rhode PR, Leong JW, Schappe T, Jewell BA, Keppel CR, Shah K, Hess B, Romee R, Piwnica-Worms DR, Cashen AF, Bartlett NL, Wong HC, Fehniger TA. Rosario M, et al. Among authors: kong l. Clin Cancer Res. 2016 Feb 1;22(3):596-608. doi: 10.1158/1078-0432.CCR-15-1419. Epub 2015 Sep 30. Clin Cancer Res. 2016. PMID: 26423796 Free PMC article.
Bifunctional TGF-β trap/IL-15 protein complex elicits potent NK cell and CD8+ T cell immunity against solid tumors.
Liu B, Zhu X, Kong L, Wang M, Spanoudis C, Chaturvedi P, George V, Jiao JA, You L, Egan JO, Echeverri C, Gallo VL, Xing J, Ravelo K, Prendes C, Antolinez J, Denissova J, Muniz GJ, Jeng EK, Rhode PR, Wong HC. Liu B, et al. Among authors: kong l. Mol Ther. 2021 Oct 6;29(10):2949-2962. doi: 10.1016/j.ymthe.2021.06.001. Epub 2021 Jun 4. Mol Ther. 2021. PMID: 34091051 Free PMC article.
8,392 results