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Page 1
APOE and immunity: Research highlights.
Kloske CM, Barnum CJ, Batista AF, Bradshaw EM, Brickman AM, Bu G, Dennison J, Gearon MD, Goate AM, Haass C, Heneka MT, Hu WT, Huggins LKL, Jones NS, Koldamova R, Lemere CA, Liddelow SA, Marcora E, Marsh SE, Nielsen HM, Petersen KK, Petersen M, Piña-Escudero SD, Qiu WQ, Quiroz YT, Reiman E, Sexton C, Tansey MG, Tcw J, Teunissen CE, Tijms BM, van der Kant R, Wallings R, Weninger SC, Wharton W, Wilcock DM, Wishard TJ, Worley SL, Zetterberg H, Carrillo MC. Kloske CM, et al. Among authors: van der kant r. Alzheimers Dement. 2023 Jun;19(6):2677-2696. doi: 10.1002/alz.13020. Epub 2023 Mar 28. Alzheimers Dement. 2023. PMID: 36975090 Review.
Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference.
Kloske CM, Belloy ME, Blue EE, Bowman GR, Carrillo MC, Chen X, Chiba-Falek O, Davis AA, Paolo GD, Garretti F, Gate D, Golden LR, Heinecke JW, Herz J, Huang Y, Iadecola C, Johnson LA, Kanekiyo T, Karch CM, Khvorova A, Koppes-den Hertog SJ, Lamb BT, Lawler PE, Guen YL, Litvinchuk A, Liu CC, Mahinrad S, Marcora E, Marino C, Michaelson DM, Miller JJ, Morganti JM, Narayan PS, Naslavsky MS, Oosthoek M, Ramachandran KV, Ramakrishnan A, Raulin AC, Robert A, Saleh RNM, Sexton C, Shah N, Shue F, Sible IJ, Soranno A, Strickland MR, Tcw J, Thierry M, Tsai LH, Tuckey RA, Ulrich JD, van der Kant R, Wang N, Wellington CL, Weninger SC, Yassine HN, Zhao N, Bu G, Goate AM, Holtzman DM. Kloske CM, et al. Among authors: van der kant r. Alzheimers Dement. 2024 Sep;20(9):6590-6605. doi: 10.1002/alz.13877. Epub 2024 Jul 19. Alzheimers Dement. 2024. PMID: 39031528 Free PMC article. Review.
Challenges and Opportunities for Consideration of Efavirenz Drug Repurposing for Alzheimer's Disease Therapeutics.
Boyarko B, Podvin S, Greenberg B, Arnold S, Juanes AM, van der Kant R, Goldstein L, Momper JD, Bang A, Silverman J, Feldman HH, Hook V. Boyarko B, et al. Among authors: van der kant r. ACS Pharmacol Transl Sci. 2024 Sep 6;7(10):2924-2935. doi: 10.1021/acsptsci.4c00229. eCollection 2024 Oct 11. ACS Pharmacol Transl Sci. 2024. PMID: 39421657 Review.
Emergence of the B.1.214.2 SARS-CoV-2 lineage with an Omicron-like spike insertion and a unique upper airway immune signature.
Holtz A, Van Weyenbergh J, Hong SL, Cuypers L, O'Toole Á, Dudas G, Gerdol M, Potter BI, Ntoumi F, Mapanguy CCM, Vanmechelen B, Wawina-Bokalanga T, Van Holm B, Menezes SM, Soubotko K, Van Pottelbergh G, Wollants E, Vermeersch P, Jacob AS, Maes B, Obbels D, Matheeussen V, Martens G, Gras J, Verhasselt B, Laffut W, Vael C, Goegebuer T, van der Kant R, Rousseau F, Schymkowitz J, Serrano L, Delgado J, Wenseleers T, Bours V, André E, Suchard MA, Rambaut A, Dellicour S, Maes P, Durkin K, Baele G. Holtz A, et al. Among authors: van der kant r. BMC Infect Dis. 2024 Oct 10;24(1):1139. doi: 10.1186/s12879-024-09967-w. BMC Infect Dis. 2024. PMID: 39390446 Free PMC article.
The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4.
Feringa FM, Hertog SJK, Wang L, Derks RJE, Kruijff I, Erlebach L, Heijneman J, Miramontes R, Pömpner N, Blomberg N, Olivier-Jimenez D, Johansen LE, Cammack AJ, Giblin A, Toomey CE, Rose IVL, Yuan H, Ward M, Isaacs AM, Kampmann M, Kronenberg-Versteeg D, Lashley T, Thompson LM, Ori A, Mohammed Y, Giera M, van der Kant R. Feringa FM, et al. Among authors: van der kant r. bioRxiv [Preprint]. 2024 Jul 3:2024.07.01.601474. doi: 10.1101/2024.07.01.601474. bioRxiv. 2024. PMID: 39005258 Free PMC article. Preprint.
An inside job: New roles for ApoE at the lipid droplet.
Feringa FM, van der Kant R. Feringa FM, et al. Among authors: van der kant r. J Cell Biol. 2024 Apr 1;223(4):e202402171. doi: 10.1083/jcb.202402171. Epub 2024 Mar 11. J Cell Biol. 2024. PMID: 38466168 Free PMC article.
Author Correction: Reverse engineering synthetic antiviral amyloids.
Michiels E, Roose K, Gallardo R, Khodaparast L, Khodaparast L, van der Kant R, Siemons M, Houben B, Ramakers M, Wilkinson H, Guerreiro P, Louros N, Kaptein SJF, Ibañez LI, Smet A, Baatsen P, Liu S, Vorberg I, Bormans G, Neyts J, Saelens X, Rousseau F, Schymkowitz J. Michiels E, et al. Among authors: van der kant r. Nat Commun. 2023 Jun 13;14(1):3492. doi: 10.1038/s41467-023-39293-9. Nat Commun. 2023. PMID: 37311856 Free PMC article. No abstract available.
Reduced Levels of Misfolded and Aggregated Mutant p53 by Proteostatic Activation.
Naus E, Derweduwe M, Lampi Y, Claeys A, Pauwels J, Langenberg T, Claes F, Xu J, Haemels V, Atak ZK, van der Kant R, Van Durme J, De Baets G, Ligon KL, Fiers M, Gevaert K, Aerts S, Rousseau F, Schymkowitz J, De Smet F. Naus E, et al. Among authors: van der kant r. Cells. 2023 Mar 21;12(6):960. doi: 10.3390/cells12060960. Cells. 2023. PMID: 36980299 Free PMC article.
Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein.
Janssen K, Claes F, Van de Velde D, Wehbi VL, Houben B, Lampi Y, Nys M, Khodaparast L, Khodaparast L, Louros N, van der Kant R, Verniers J, Garcia T, Ramakers M, Konstantoulea K, Maragkou K, Duran-Romaña R, Musteanu M, Barbacid M, Scorneaux B, Beirnaert E, Schymkowitz J, Rousseau F. Janssen K, et al. Among authors: van der kant r. Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2214921120. doi: 10.1073/pnas.2214921120. Epub 2023 Feb 22. Proc Natl Acad Sci U S A. 2023. PMID: 36812200 Free PMC article.
A reference human induced pluripotent stem cell line for large-scale collaborative studies.
Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, Pratt G, Cross E, Blockwick J, Buxton P, Kinner-Bibeau L, Medura C, Tompkins C, Hughes S, Santiana M, Faghri F, Nalls MA, Vitale D, Ballard S, Qi YA, Ramos DM, Anderson KM, Stadler J, Narayan P, Papademetriou J, Reilly L, Nelson MP, Aggarwal S, Rosen LU, Kirwan P, Pisupati V, Coon SL, Scholz SW, Priebe T, Öttl M, Dong J, Meijer M, Janssen LJM, Lourenco VS, van der Kant R, Crusius D, Paquet D, Raulin AC, Bu G, Held A, Wainger BJ, Gabriele RMC, Casey JM, Wray S, Abu-Bonsrah D, Parish CL, Beccari MS, Cleveland DW, Li E, Rose IVL, Kampmann M, Calatayud Aristoy C, Verstreken P, Heinrich L, Chen MY, Schüle B, Dou D, Holzbaur ELF, Zanellati MC, Basundra R, Deshmukh M, Cohen S, Khanna R, Raman M, Nevin ZS, Matia M, Van Lent J, Timmerman V, Conklin BR, Johnson Chase K, Zhang K, Funes S, Bosco DA, Erlebach L, Welzer M, Kronenberg-Versteeg D, Lyu G, Arenas E, Coccia E, Sarrafha L, Ahfeldt T, Marioni JC, Skarnes WC, Cookson MR, Ward ME, Merkle FT. Pantazis CB, et al. Among authors: van der kant r. Cell Stem Cell. 2022 Dec 1;29(12):1685-1702.e22. doi: 10.1016/j.stem.2022.11.004. Cell Stem Cell. 2022. PMID: 36459969 Free PMC article.
47 results