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Chronic immune activation and gut barrier dysfunction is associated with neuroinflammation in ART-suppressed SIV+ rhesus macaques.
Byrnes SJ, Busman-Sahay K, Angelovich TA, Younger S, Taylor-Brill S, Nekorchuk M, Bondoc S, Dannay R, Terry M, Cochrane CR, Jenkins TA, Roche M, Deleage C, Bosinger SE, Paiardini M, Brew BJ, Estes JD, Churchill MJ. Byrnes SJ, et al. Among authors: brew bj. PLoS Pathog. 2023 Mar 29;19(3):e1011290. doi: 10.1371/journal.ppat.1011290. eCollection 2023 Mar. PLoS Pathog. 2023. PMID: 36989320 Free PMC article.
HIV transcription persists in the brain of virally suppressed people with HIV.
Jamal Eddine J, Angelovich TA, Zhou J, Byrnes SJ, Tumpach C, Saraya N, Chalmers E, Shepherd RA, Tan A, Marinis S, Gorry PR, Estes JD, Brew BJ, Lewin SR, Telwatte S, Roche M, Churchill MJ. Jamal Eddine J, et al. Among authors: brew bj. PLoS Pathog. 2024 Aug 8;20(8):e1012446. doi: 10.1371/journal.ppat.1012446. eCollection 2024 Aug. PLoS Pathog. 2024. PMID: 39116185 Free PMC article.
Reversible large-scale network disruption correlates with neurocognitive improvement in HIV-associated minor neurocognitive disorder with combined anti-retroviral therapy intensification: a prospective longitudinal resting-state functional magnetic resonance imaging study.
Chaganti J, Gates TM, Brew BJ. Chaganti J, et al. Among authors: brew bj. Neurol Sci. 2023 Sep;44(9):3261-3269. doi: 10.1007/s10072-023-06783-z. Epub 2023 Apr 13. Neurol Sci. 2023. PMID: 37052787
Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection.
Phetsouphanh C, Jacka B, Ballouz S, Jackson KJL, Wilson DB, Manandhar B, Klemm V, Tan HX, Wheatley A, Aggarwal A, Akerman A, Milogiannakis V, Starr M, Cunningham P, Turville SG, Kent SJ, Byrne A, Brew BJ, Darley DR, Dore GJ, Kelleher AD, Matthews GV. Phetsouphanh C, et al. Among authors: brew bj. Nat Commun. 2024 Apr 17;15(1):3315. doi: 10.1038/s41467-024-47720-8. Nat Commun. 2024. PMID: 38632311 Free PMC article.
Blood brain barrier disruption and glutamatergic excitotoxicity in post-acute sequelae of SARS COV-2 infection cognitive impairment: potential biomarkers and a window into pathogenesis.
Chaganti J, Poudel G, Cysique LA, Dore GJ, Kelleher A, Matthews G, Darley D, Byrne A, Jakabek D, Zhang X, Lewis M, Jha N, Brew BJ. Chaganti J, et al. Among authors: brew bj. Front Neurol. 2024 May 2;15:1350848. doi: 10.3389/fneur.2024.1350848. eCollection 2024. Front Neurol. 2024. PMID: 38756214 Free PMC article.
Fostering healthy cognitive ageing in people living with HIV.
Cysique LA, Levin J, Howard C, Taylor J, Rule J, Costello J, Bruning J, Njeri P, Mullens AB, Wright E, Gouse H, Daken K, Trunfio M, Aung HL, Robbins RN, Ferraris CM, Muñoz-Moreno JA, Woods SP, Moore DJ, Power C, Wong PL, Hasmukharay K, Nyamayaro P, Vera J, Rajasuriar R, Heaton RK, Goodkin K, Letendre S, Ellis RJ, Brew BJ, Rourke SB; NeuroHIV and Aging Advocacy Group. Cysique LA, et al. Among authors: brew bj. Lancet HIV. 2025 Jan;12(1):e71-e80. doi: 10.1016/S2352-3018(24)00248-0. Epub 2024 Nov 29. Lancet HIV. 2025. PMID: 39615509
342 results