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Genome-wide Studies Reveal Genetic Risk Factors for Hepatic Fat Content.
Li Y, van den Berg EH, Kurilshikov A, Zhernakova DV, Gacesa R, Hu S, Lopera-Maya EA, Zhernakova A; Lifelines Cohort Study; de Meijer VE, Sanna S, Dullaart RPF, Blokzijl H, Festen EAM, Fu J, Weersma RK. Li Y, et al. Genomics Proteomics Bioinformatics. 2024 Jul 3;22(2):qzae031. doi: 10.1093/gpbjnl/qzae031. Genomics Proteomics Bioinformatics. 2024. PMID: 39142818 Free article.
Co-expression in tissue-specific gene networks links genes in cancer-susceptibility loci to known somatic driver genes.
Urzúa-Traslaviña CG, van Lieshout T, Boulogne F, Domanegg K, Zidan M, Bakker OB, Claringbould A, de Ridder J, Zwart W, Westra HJ, Deelen P, Franke L. Urzúa-Traslaviña CG, et al. Among authors: deelen p. BMC Med Genomics. 2024 Jul 15;17(1):186. doi: 10.1186/s12920-024-01941-4. BMC Med Genomics. 2024. PMID: 39010058 Free PMC article.
Multi-ancestry polygenic risk scores for venous thromboembolism.
Jee YH, Thibord F, Dominguez A, Sept C, Boulier K, Venkateswaran V, Ding Y, Cherlin T, Verma SS, Faro VL, Bartz TM, Boland A, Brody JA, Deleuze JF, Emmerich J, Germain M, Johnson AD, Kooperberg C, Morange PE, Pankratz N, Psaty BM, Reiner AP, Smadja DM, Sitlani CM, Suchon P, Tang W, Trégouët DA, Zöllner S, Pasaniuc B, Damrauer SM, Sanna S, Snieder H; Lifelines Cohort Study; Kabrhel C, Smith NL, Kraft P; INVENT Consortium. Jee YH, et al. Hum Mol Genet. 2024 Sep 3;33(18):1584-1591. doi: 10.1093/hmg/ddae097. Hum Mol Genet. 2024. PMID: 38879759
Leveraging functional genomic annotations and genome coverage to improve polygenic prediction of complex traits within and between ancestries.
Zheng Z, Liu S, Sidorenko J, Wang Y, Lin T, Yengo L, Turley P, Ani A, Wang R, Nolte IM, Snieder H; LifeLines Cohort Study; Yang J, Wray NR, Goddard ME, Visscher PM, Zeng J. Zheng Z, et al. Nat Genet. 2024 May;56(5):767-777. doi: 10.1038/s41588-024-01704-y. Epub 2024 Apr 30. Nat Genet. 2024. PMID: 38689000 Free PMC article.
Comprehensive evaluation of smoking exposures and their interactions on DNA methylation.
Hoang TT, Lee Y, McCartney DL, Kersten ETG, Page CM, Hulls PM, Lee M, Walker RM, Breeze CE, Bennett BD, Burkholder AB, Ward J, Brantsæter AL, Caspersen IH, Motsinger-Reif AA, Richards M, White JD, Zhao S, Richmond RC, Magnus MC; BIOS Consortium; Koppelman GH, Evans KL, Marioni RE, Håberg SE, London SJ. Hoang TT, et al. EBioMedicine. 2024 Feb;100:104956. doi: 10.1016/j.ebiom.2023.104956. Epub 2024 Jan 9. EBioMedicine. 2024. PMID: 38199042 Free PMC article.
128 results