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Page 1
G-CSF drives autoinflammation in APLAID.
Mulazzani E, Kong K, Aróstegui JI, Ng AP, Ranathunga N, Abeysekera W, Garnham AL, Ng SL, Baker PJ, Jackson JT, Lich JD, Hibbs ML, Wicks IP, Louis C, Masters SL. Mulazzani E, et al. Among authors: masters sl. Nat Immunol. 2023 May;24(5):814-826. doi: 10.1038/s41590-023-01473-6. Epub 2023 Mar 30. Nat Immunol. 2023. PMID: 36997670 Free PMC article.
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.
Lawlor KE, Khan N, Mildenhall A, Gerlic M, Croker BA, D'Cruz AA, Hall C, Kaur Spall S, Anderton H, Masters SL, Rashidi M, Wicks IP, Alexander WS, Mitsuuchi Y, Benetatos CA, Condon SM, Wong WW, Silke J, Vaux DL, Vince JE. Lawlor KE, et al. Among authors: masters sl. Nat Commun. 2015 Feb 18;6:6282. doi: 10.1038/ncomms7282. Nat Commun. 2015. PMID: 25693118 Free PMC article.
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-4 and caspase-5.
Baker PJ, Boucher D, Bierschenk D, Tebartz C, Whitney PG, D'Silva DB, Tanzer MC, Monteleone M, Robertson AA, Cooper MA, Alvarez-Diaz S, Herold MJ, Bedoui S, Schroder K, Masters SL. Baker PJ, et al. Among authors: masters sl. Eur J Immunol. 2015 Oct;45(10):2918-26. doi: 10.1002/eji.201545655. Epub 2015 Aug 24. Eur J Immunol. 2015. PMID: 26173988 Free article.
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation.
Masters SL, Lagou V, Jéru I, Baker PJ, Van Eyck L, Parry DA, Lawless D, De Nardo D, Garcia-Perez JE, Dagley LF, Holley CL, Dooley J, Moghaddas F, Pasciuto E, Jeandel PY, Sciot R, Lyras D, Webb AI, Nicholson SE, De Somer L, van Nieuwenhove E, Ruuth-Praz J, Copin B, Cochet E, Medlej-Hashim M, Megarbane A, Schroder K, Savic S, Goris A, Amselem S, Wouters C, Liston A. Masters SL, et al. Sci Transl Med. 2016 Mar 30;8(332):332ra45. doi: 10.1126/scitranslmed.aaf1471. Sci Transl Med. 2016. PMID: 27030597 Free article.
A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever.
Moghaddas F, Llamas R, De Nardo D, Martinez-Banaclocha H, Martinez-Garcia JJ, Mesa-Del-Castillo P, Baker PJ, Gargallo V, Mensa-Vilaro A, Canna S, Wicks IP, Pelegrin P, Arostegui JI, Masters SL. Moghaddas F, et al. Among authors: masters sl. Ann Rheum Dis. 2017 Dec;76(12):2085-2094. doi: 10.1136/annrheumdis-2017-211473. Epub 2017 Aug 23. Ann Rheum Dis. 2017. PMID: 28835462 Free PMC article.
SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition.
Nguyen TA, Smith BRC, Tate MD, Belz GT, Barrios MH, Elgass KD, Weisman AS, Baker PJ, Preston SP, Whitehead L, Garnham A, Lundie RJ, Smyth GK, Pellegrini M, O'Keeffe M, Wicks IP, Masters SL, Hunter CP, Pang KC. Nguyen TA, et al. Among authors: masters sl. Immunity. 2017 Sep 19;47(3):498-509.e6. doi: 10.1016/j.immuni.2017.08.007. Epub 2017 Sep 12. Immunity. 2017. PMID: 28916264 Free PMC article.
167 results