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DNA lipid nanoparticle vaccine targeting outer surface protein C affords protection against homologous Borrelia burgdorferi needle challenge in mice.
Pfeifle A, Thulasi Raman SN, Lansdell C, Zhang W, Tamming L, Cecillon J, Laryea E, Patel D, Wu J, Gravel C, Frahm G, Gao J, Chen W, Chaconas G, Sauve S, Rosu-Myles M, Wang L, Johnston MJW, Li X. Pfeifle A, et al. Among authors: chen w. Front Immunol. 2023 Mar 16;14:1020134. doi: 10.3389/fimmu.2023.1020134. eCollection 2023. Front Immunol. 2023. PMID: 37006299 Free PMC article.
Bivalent vaccines effectively protect mice against influenza A and respiratory syncytial viruses.
Raman SNT, Zetner A, Hashem AM, Patel D, Wu J, Gravel C, Gao J, Zhang W, Pfeifle A, Tamming L, Parikh K, Cao J, Tam R, Safronetz D, Chen W, Johnston MJW, Wang L, Sauve S, Rosu-Myles M, Domselaar GV, Li X. Raman SNT, et al. Among authors: chen w. Emerg Microbes Infect. 2023 Dec;12(1):2192821. doi: 10.1080/22221751.2023.2192821. Emerg Microbes Infect. 2023. PMID: 36927227 Free PMC article.
Novel recombinant vaccinia virus-vectored vaccine affords complete protection against homologous Borrelia burgdorferi infection in mice.
Pfeifle A, Zhang W, Cao J, Thulasi Raman SN, Anderson-Duvall R, Tamming L, Gravel C, Coatsworth H, Chen W, Johnston MJW, Sauve S, Rosu-Myles M, Wang L, Li X. Pfeifle A, et al. Among authors: chen w. Emerg Microbes Infect. 2024 Dec;13(1):2399949. doi: 10.1080/22221751.2024.2399949. Epub 2024 Oct 11. Emerg Microbes Infect. 2024. PMID: 39221484 Free PMC article.
Lipid nanoparticle encapsulation of a Delta spike-CD40L DNA vaccine improves effectiveness against Omicron challenge in Syrian hamsters.
Tamming L, Duque D, Tran A, Lansdell C, Frahm G, Wu J, Fekete EEF, Creskey M, Thulasi Raman SN, Laryea E, Zhang W, Pfeifle A, Gravel C, Stalker A, Hashem AM, Chen W, Stuible M, Durocher Y, Safronetz D, Cao J, Wang L, Sauve S, Rosu-Myles M, Zhang X, Johnston MJW, Li X. Tamming L, et al. Among authors: chen w. Mol Ther Methods Clin Dev. 2024 Aug 19;32(3):101325. doi: 10.1016/j.omtm.2024.101325. eCollection 2024 Sep 12. Mol Ther Methods Clin Dev. 2024. PMID: 39309757 Free PMC article.
Dissecting immunological mechanisms underlying influenza viral nucleoprotein-induced mucosal immunity against diverse viral strains.
Zhang W, Sloan A, Prévost J, Tamming L, Raman S, Pfeifle A, Gravel C, Chen W, Hashem AM, Wu J, Cao J, Johnston MJW, Wang L, Sauve S, Rosu-Myles M, Kobasa D, Safronetz D, Li X. Zhang W, et al. Among authors: chen w. Emerg Microbes Infect. 2024 Dec;13(1):2427792. doi: 10.1080/22221751.2024.2427792. Epub 2024 Nov 21. Emerg Microbes Infect. 2024. PMID: 39508450 Free PMC article.
Functional domains of Acinetobacter bacteriophage tail fibers.
Peters DL, Gaudreault F, Chen W. Peters DL, et al. Among authors: chen w. Front Microbiol. 2024 Apr 16;15:1230997. doi: 10.3389/fmicb.2024.1230997. eCollection 2024. Front Microbiol. 2024. PMID: 38690360 Free PMC article.
Tenecteplase Thrombolysis for Stroke up to 24 Hours After Onset With Perfusion Imaging Selection: The CHABLIS-T II Randomized Clinical Trial.
Cheng X, Hong L, Lin L, Churilov L, Ling Y, Yang N, Fu J, Lu G, Yue Y, Zhang J, Wang F, Wang Z, Zhao Y, Zhou X, Peng Z, Wu D, Zhao L, Zhai Q, Yu X, Fang Q, Shao X, Tang Y, Zhang D, Geng Y, Zhang Y, Fan B, Zhang B, Yin C, Chen Y, Zhang Y, Liu X, Li S, Yang L, Parsons M, Dong Q; CHABLIS-T II Collaborators. Cheng X, et al. Stroke. 2025 Jan 2. doi: 10.1161/STROKEAHA.124.048375. Online ahead of print. Stroke. 2025. PMID: 39744861
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