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791 results

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Page 1
AIntibody: an experimentally validated in silico antibody discovery design challenge.
Erasmus MF, Spector L, Ferrara F, DiNiro R, Pohl TJ, Perea-Schmittle K, Wang W, Tessier PM, Richardson C, Turner L, Kumar S, Bedinger D, Sormanni P, Fernández-Quintero ML, Ward AB, Loeffler JR, Swanson OM, Deane CM, Raybould MIJ, Evers A, Sellmann C, Bachas S, Ruffolo J, Nastri HG, Ramesh K, Sørensen J, Croasdale-Wood R, Hijano O, Leal-Lopes C, Shahsavarian M, Qiu Y, Marcatili P, Vernet E, Akbar R, Friedensohn S, Wagner R, Kurella VB, Malhotra S, Kumar S, Kidger P, Almagro JC, Furfine E, Stanton M, Graff CP, Villalba SD, Tomszak F, Teixeira AAR, Hopkins E, Dovner M, D'Angelo S, Bradbury ARM. Erasmus MF, et al. Among authors: loeffler jr. Nat Biotechnol. 2024 Nov 4. doi: 10.1038/s41587-024-02469-9. Online ahead of print. Nat Biotechnol. 2024. PMID: 39496931 No abstract available.
CosolvKit: a Versatile Tool for Cosolvent MD Preparation and Analysis.
Bruciaferri N, Eberhardt J, Llanos MA, Loeffler JR, Holcomb M, Fernandez-Quintero ML, Santos-Martins D, Ward AB, Forli S. Bruciaferri N, et al. Among authors: loeffler jr. J Chem Inf Model. 2024 Oct 22. doi: 10.1021/acs.jcim.4c01398. Online ahead of print. J Chem Inf Model. 2024. PMID: 39436011
On the humanization of VHHs: Prospective case studies, experimental and computational characterization of structural determinants for functionality.
Fernández-Quintero ML, Guarnera E, Musil D, Pekar L, Sellmann C, Freire F, Sousa RL, Santos SP, Freitas MC, Bandeiras TM, Silva MMS, Loeffler JR, Ward AB, Harwardt J, Zielonka S, Evers A. Fernández-Quintero ML, et al. Among authors: loeffler jr. Protein Sci. 2024 Nov;33(11):e5176. doi: 10.1002/pro.5176. Protein Sci. 2024. PMID: 39422475 Free PMC article.
Impact of essential genes on the success of genome editing experiments generating 3313 new genetically engineered mouse lines.
Elrick H, Peterson KA, Willis BJ, Lanza DG, Acar EF, Ryder EJ, Teboul L, Kasparek P, Birling MC, Adams DJ, Bradley A, Braun RE, Brown SD, Caulder A, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Duddy G, Gertsenstein M, Goodwin LO, Hérault Y, Lintott LG, Lloyd KCK, Lorenzo I, Mackenzie M, Mallon AM, McKerlie C, Parkinson H, Ramirez-Solis R, Seavitt JR, Sedlacek R, Skarnes WC, Smedley D, Wells S, White JK, Wood JA; International Mouse Phenotyping Consortium; Murray SA, Heaney JD, Nutter LMJ. Elrick H, et al. Sci Rep. 2024 Sep 30;14(1):22626. doi: 10.1038/s41598-024-72418-8. Sci Rep. 2024. PMID: 39349521 Free PMC article.
Assessing AF2's ability to predict structural ensembles of proteins.
Riccabona JR, Spoendlin FC, Fischer AM, Loeffler JR, Quoika PK, Jenkins TP, Ferguson JA, Smorodina E, Laustsen AH, Greiff V, Forli S, Ward AB, Deane CM, Fernández-Quintero ML. Riccabona JR, et al. Among authors: loeffler jr. Structure. 2024 Sep 20:S0969-2126(24)00370-8. doi: 10.1016/j.str.2024.09.001. Online ahead of print. Structure. 2024. PMID: 39332396
Functional microanatomy of the vomeronasal complex of bats.
Smith TD, Downing SE, Rosenberger VB, Loeffler JR, King NA, Curtis AA, Eiting TP, Santana SE. Smith TD, et al. Among authors: loeffler jr. Anat Rec (Hoboken). 2024 Aug 13. doi: 10.1002/ar.25557. Online ahead of print. Anat Rec (Hoboken). 2024. PMID: 39136383
CD56-mediated activation of human natural killer cells is triggered by Aspergillus fumigatus galactosaminogalactan.
Heilig L, Natasha F, Trinks N, Aimanianda V, Wong SSW, Fontaine T, Terpitz U, Strobel L, Le Mauff F, Sheppard DC, Schäuble S, Kurzai O, Hünniger K, Weiss E, Vargas M, Howell PL, Panagiotou G, Wurster S, Einsele H, Loeffler J. Heilig L, et al. Among authors: loeffler j. PLoS Pathog. 2024 Jun 18;20(6):e1012315. doi: 10.1371/journal.ppat.1012315. eCollection 2024 Jun. PLoS Pathog. 2024. PMID: 38889192 Free PMC article.
Polymerase Chain Reaction on Respiratory Tract Specimens of Immunocompromised Patients to Diagnose Pneumocystis Pneumonia: A Systematic Review and Meta-analysis.
Brown L, Rautemaa-Richardson R, Mengoli C, Alanio A, Barnes RA, Bretagne S, Chen SCA, Cordonnier C, Donnelly JP, Heinz WJ, Jones B, Klingspor L, Loeffler J, Rogers TR, Rowbotham E, White PL, Cruciani M. Brown L, et al. Among authors: loeffler j. Clin Infect Dis. 2024 Jul 19;79(1):161-168. doi: 10.1093/cid/ciae239. Clin Infect Dis. 2024. PMID: 38860786 Free PMC article. Review.
791 results