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Validating organoid-derived human intestinal monolayers for personalized therapy in cystic fibrosis.
Birimberg-Schwartz L, Ip W, Bartlett C, Avolio J, Vonk AM, Gunawardena T, Du K, Esmaeili M, Beekman JM, Rommens J, Strug L, Bear CE, Moraes TJ, Gonska T. Birimberg-Schwartz L, et al. Among authors: beekman jm. Life Sci Alliance. 2023 Apr 5;6(6):e202201857. doi: 10.26508/lsa.202201857. Print 2023 Jun. Life Sci Alliance. 2023. PMID: 37024122 Free PMC article.
PPARγ as a therapeutic target in cystic fibrosis.
Dekkers JF, van der Ent CK, Kalkhoven E, Beekman JM. Dekkers JF, et al. Among authors: beekman jm. Trends Mol Med. 2012 May;18(5):283-91. doi: 10.1016/j.molmed.2012.03.004. Epub 2012 Apr 9. Trends Mol Med. 2012. PMID: 22494945 Review.
Optimal complement-mediated phagocytosis of Pseudomonas aeruginosa by monocytes is cystic fibrosis transmembrane conductance regulator-dependent.
Van de Weert-van Leeuwen PB, Van Meegen MA, Speirs JJ, Pals DJ, Rooijakkers SH, Van der Ent CK, Terheggen-Lagro SW, Arets HG, Beekman JM. Van de Weert-van Leeuwen PB, et al. Among authors: beekman jm. Am J Respir Cell Mol Biol. 2013 Sep;49(3):463-70. doi: 10.1165/rcmb.2012-0502OC. Am J Respir Cell Mol Biol. 2013. PMID: 23617438
A functional CFTR assay using primary cystic fibrosis intestinal organoids.
Dekkers JF, Wiegerinck CL, de Jonge HR, Bronsveld I, Janssens HM, de Winter-de Groot KM, Brandsma AM, de Jong NW, Bijvelds MJ, Scholte BJ, Nieuwenhuis EE, van den Brink S, Clevers H, van der Ent CK, Middendorp S, Beekman JM. Dekkers JF, et al. Among authors: beekman jm. Nat Med. 2013 Jul;19(7):939-45. doi: 10.1038/nm.3201. Epub 2013 Jun 2. Nat Med. 2013. PMID: 23727931
CFTR functional measurements in human models for diagnosis, prognosis and personalized therapy: Report on the pre-conference meeting to the 11th ECFS Basic Science Conference, Malta, 26-29 March 2014.
Beekman JM, Sermet-Gaudelus I, de Boeck K, Gonska T, Derichs N, Mall MA, Mehta A, Martin U, Drumm M, Amaral MD. Beekman JM, et al. J Cyst Fibros. 2014 Jul;13(4):363-72. doi: 10.1016/j.jcf.2014.05.007. Epub 2014 Jun 2. J Cyst Fibros. 2014. PMID: 24882694 Free article. Review. No abstract available.
132 results