Obst R - Search Results

1

Phosphatidylserine-positive extracellular vesicles boost effector CD8⁺ T cell responses during viral infection.

Rausch L, Flaskamp L, Ashokkumar A, Trefzer A, Ried C, Buchholz VR, Obst R, Straub T, Brocker T, Kranich J. Rausch L, et al. Among authors: obst r. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2210047120. doi: 10.1073/pnas.2210047120. Epub 2023 Apr 11. Proc Natl Acad Sci U S A. 2023. PMID: 37040405 Free PMC article.

2

Priming of cytotoxic T lymphocytes by five heat-aggregated antigens in vivo: conditions, efficiency, and relation to antibody responses.

Speidel K, Osen W, Faath S, Hilgert I, Obst R, Braspenning J, Momburg F, Hämmerling GJ, Rammensee HG. Speidel K, et al. Among authors: obst r. Eur J Immunol. 1997 Sep;27(9):2391-9. doi: 10.1002/eji.1830270938. Eur J Immunol. 1997. PMID: 9341785

3

Role of antigen persistence and dose for CD4+ T-cell exhaustion and recovery.

Han S, Asoyan A, Rabenstein H, Nakano N, Obst R. Han S, et al. Among authors: obst r. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20453-8. doi: 10.1073/pnas.1008437107. Epub 2010 Nov 8. Proc Natl Acad Sci U S A. 2010. PMID: 21059929 Free PMC article.

4

Differential kinetics of antigen dependency of CD4+ and CD8+ T cells.

Rabenstein H, Behrendt AC, Ellwart JW, Naumann R, Horsch M, Beckers J, Obst R. Rabenstein H, et al. Among authors: obst r. J Immunol. 2014 Apr 15;192(8):3507-17. doi: 10.4049/jimmunol.1302725. Epub 2014 Mar 17. J Immunol. 2014. PMID: 24639353

5

Dynamic adoption of anergy by antigen-exhausted CD4⁺ T cells.

Trefzer A, Kadam P, Wang SH, Pennavaria S, Lober B, Akçabozan B, Kranich J, Brocker T, Nakano N, Irmler M, Beckers J, Straub T, Obst R. Trefzer A, et al. Among authors: obst r. Cell Rep. 2021 Feb 9;34(6):108748. doi: 10.1016/j.celrep.2021.108748. Cell Rep. 2021. PMID: 33567282 Free article.

6

Reciprocal regulation of mTORC1 signaling and ribosomal biosynthesis determines cell cycle progression in activated T cells.

Rosenlehner T, Pennavaria S, Akçabozan B, Jahani S, O'Neill TJ, Krappmann D, Straub T, Kranich J, Obst R. Rosenlehner T, et al. Among authors: obst r. Sci Signal. 2024 Oct 22;17(859):eadi8753. doi: 10.1126/scisignal.adi8753. Epub 2024 Oct 22. Sci Signal. 2024. PMID: 39436996

7

Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation.

Obst R, van Santen HM, Melamed R, Kamphorst AO, Benoist C, Mathis D. Obst R, et al. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15460-5. doi: 10.1073/pnas.0707331104. Epub 2007 Sep 19. Proc Natl Acad Sci U S A. 2007. PMID: 17881563 Free PMC article.

8

The Timing of T Cell Priming and Cycling.

Obst R. Obst R. Front Immunol. 2015 Nov 5;6:563. doi: 10.3389/fimmu.2015.00563. eCollection 2015. Front Immunol. 2015. PMID: 26594213 Free PMC article. Review.

9

Advanced Quantification of Receptor-Ligand Interaction Lifetimes via Single-Molecule FRET Microscopy.

Schrangl L, Mühlgrabner V, Platzer R, Kellner F, Wieland J, Obst R, Toca-Herrera JL, Huppa JB, Schütz GJ, Göhring J. Schrangl L, et al. Among authors: obst r. Biomolecules. 2024 Aug 13;14(8):1001. doi: 10.3390/biom14081001. Biomolecules. 2024. PMID: 39199389 Free PMC article.

10

Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response.

Obst R, van Santen HM, Mathis D, Benoist C. Obst R, et al. J Exp Med. 2005 May 16;201(10):1555-65. doi: 10.1084/jem.20042521. J Exp Med. 2005. PMID: 15897273 Free PMC article.

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