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The SARS-CoV-2 Alpha variant was associated with increased clinical severity of COVID-19 in Scotland: A genomics-based retrospective cohort analysis.
Pascall DJ, Vink E, Blacow R, Bulteel N, Campbell A, Campbell R, Clifford S, Davis C, da Silva Filipe A, El Sakka N, Fjodorova L, Forrest R, Goldstein E, Gunson R, Haughney J, Holden MTG, Honour P, Hughes J, James E, Lewis T, Lycett S, MacLean O, McHugh M, Mollett G, Onishi Y, Parcell B, Ray S, Robertson DL, Shabaan S, Shepherd JG, Smollett K, Templeton K, Wastnedge E, Wilkie C, Williams T, Thomson EC; COVID-19 Genomics UK (COG-UK) Consortium. Pascall DJ, et al. Among authors: fjodorova l. PLoS One. 2023 Apr 13;18(4):e0284187. doi: 10.1371/journal.pone.0284187. eCollection 2023. PLoS One. 2023. PMID: 37053201 Free PMC article.
Directions of change in intrinsic case severity across successive SARS-CoV-2 variant waves have been inconsistent.
Pascall DJ, Vink E, Blacow R, Bulteel N, Campbell A, Campbell R, Clifford S, Davis C, da Silva Filipe A, El Sakka N, Fjodorova L, Forrest R, Goldstein E, Gunson R, Haughney J, Holden MTG, Honour P, Hughes J, James E, Lewis T, MacLean O, McHugh M, Mollett G, Nyberg T, Onishi Y, Parcell B, Ray S, Robertson DL, Seaman SR, Shabaan S, Shepherd JG, Smollett K, Templeton K, Wastnedge E, Wilkie C, Williams T; COVID-19 Genomics UK (COG-UK) Consortium; Thomson EC. Pascall DJ, et al. Among authors: fjodorova l. J Infect. 2023 Aug;87(2):128-135. doi: 10.1016/j.jinf.2023.05.019. Epub 2023 Jun 1. J Infect. 2023. PMID: 37270070 Free PMC article.