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Induction of antigen specific intrahepatic CD8+ T cell responses by a secreted heat shock protein based gp96-Ig-PfCA malaria vaccine.
Padula L, Fisher E, Wijayalath W, Patterson NB, Huang J, Ganeshan H, Robinson T, Bates FA, Hanson MA, Martin ML, Rivas K, Garcia D, Edgel KA, Sedegah M, Villasante E, Strbo N. Padula L, et al. Among authors: martin ml. Front Immunol. 2023 Mar 28;14:1130054. doi: 10.3389/fimmu.2023.1130054. eCollection 2023. Front Immunol. 2023. PMID: 37056783 Free PMC article.
Optimization of a Plasmodium falciparum circumsporozoite protein repeat vaccine using the tobacco mosaic virus platform.
Langowski MD, Khan FA, Bitzer AA, Genito CJ, Schrader AJ, Martin ML, Soto K, Zou X, Hadiwidjojo S, Beck Z, Matyas GR, Livingstone MC, Batchelor AH, Dutta S. Langowski MD, et al. Among authors: martin ml. Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):3114-3122. doi: 10.1073/pnas.1911792117. Epub 2020 Jan 27. Proc Natl Acad Sci U S A. 2020. PMID: 31988134 Free PMC article.
SARS-CoV-2 recombinant spike ferritin nanoparticle vaccine adjuvanted with Army Liposome Formulation containing monophosphoryl lipid A and QS-21: a phase 1, randomised, double-blind, placebo-controlled, first-in-human clinical trial.
Ober Shepherd BL, Scott PT, Hutter JN, Lee C, McCauley MD, Guzman I, Bryant C, McGuire S, Kennedy J, Chen WH, Hajduczki A, Mdluli T, Valencia-Ruiz A, Amare MF, Matyas GR, Rao M, Rolland M, Mascola JR, De Rosa SC, McElrath MJ, Montefiori DC, Serebryannyy L, McDermott AB, Peel SA, Collins ND, Joyce MG, Robb ML, Michael NL, Vasan S, Modjarrad K; EID-030 Study Group. Ober Shepherd BL, et al. Lancet Microbe. 2024 Jun;5(6):e581-e593. doi: 10.1016/S2666-5247(23)00410-X. Epub 2024 May 15. Lancet Microbe. 2024. PMID: 38761816 Free article. Clinical Trial.
Discovery and Optimization of Tambjamines as a Novel Class of Antileishmanial Agents.
Kancharla P, Ortiz D, Fargo CM, Zhang X, Li Y, Sanchez M, Kumar A, Yeluguri M, Dodean RA, Caridha D, Madejczyk MS, Martin M, Jin X, Blount C, Chetree R, Pannone K, Dinh HT, DeLuca J, Evans M, Nadeau R, Vuong C, Leed S, Dennis WE, Roncal N, Pybus BS, Lee PJ, Roth A, Reynolds KA, Kelly JX, Landfear SM. Kancharla P, et al. J Med Chem. 2024 May 23;67(10):8323-8345. doi: 10.1021/acs.jmedchem.4c00517. Epub 2024 May 9. J Med Chem. 2024. PMID: 38722757 Free PMC article.
Tambjamines as Fast-Acting Multistage Antimalarials.
Kumar A, Li Y, Dodean RA, Roth A, Caridha D, Madejczyk MS, Jin X, Dennis WE, Lee PJ, Pybus BS, Martin M, Pannone K, Dinh HT, Blount C, Chetree R, DeLuca J, Evans M, Nadeau R, Vuong C, Leed S, Black C, Sousa J, Nolan C, Ceja FG, Rasmussen SA, Tumwebaze PK, Rosenthal PJ, Cooper RA, Rottmann M, Orjuela-Sanchez P, Meister S, Winzeler EA, Delves MJ, Matthews H, Baum J, Kirby RW, Burrows JN, Duffy J, Peyton DH, Reynolds KA, Kelly JX, Kancharla P. Kumar A, et al. ACS Infect Dis. 2024 Dec 13;10(12):4291-4300. doi: 10.1021/acsinfecdis.4c00659. Epub 2024 Nov 11. ACS Infect Dis. 2024. PMID: 39526703 Free PMC article.
505 results