An optimized IL-12-Fc expands its therapeutic window, achieving strong activity against mouse tumors at tolerable drug doses.
Gutierrez E, Bigelow M, LaCroix C, Beech J, Kirby P, Markowitz L, Shifrin M, Naill M, Braun A, O'Neil S, Cuillerot JM, Cheung A, Grinberg A, Wagtmann N.
Gutierrez E, et al. Among authors: naill m.
Med. 2023 May 12;4(5):326-340.e5. doi: 10.1016/j.medj.2023.03.007. Epub 2023 Apr 13.
Med. 2023.
PMID: 37059099
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