Johnson RJ - Search Results

1

Sequence and Structural Motifs Controlling the Broad Substrate Specificity of the Mycobacterial Hormone-Sensitive Lipase LipN.

Schemenauer DE, Pool EH, Raynor SN, Ruiz GP, Goehring LM, Koelper AJ, Wilson MA, Durand AJ Jr, Kourtoglou EC, Larsen EM, Lavis LD, Esteb JJ, Hoops GC, Johnson RJ. Schemenauer DE, et al. Among authors: johnson rj. ACS Omega. 2023 Mar 30;8(14):13252-13264. doi: 10.1021/acsomega.3c00534. eCollection 2023 Apr 11. ACS Omega. 2023. PMID: 37065048 Free PMC article.

2

Cytotoxic ribonucleases: the dichotomy of Coulombic forces.

Johnson RJ, Chao TY, Lavis LD, Raines RT. Johnson RJ, et al. Biochemistry. 2007 Sep 11;46(36):10308-16. doi: 10.1021/bi700857u. Epub 2007 Aug 18. Biochemistry. 2007. PMID: 17705507 Free PMC article.

3

Intraspecies regulation of ribonucleolytic activity.

Johnson RJ, Lavis LD, Raines RT. Johnson RJ, et al. Biochemistry. 2007 Nov 13;46(45):13131-40. doi: 10.1021/bi701521q. Epub 2007 Oct 23. Biochemistry. 2007. PMID: 17956129 Free PMC article.

4

The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima.

Hedge MK, Gehring AM, Adkins CT, Weston LA, Lavis LD, Johnson RJ. Hedge MK, et al. Among authors: johnson rj. Biochim Biophys Acta. 2012 Sep;1824(9):1024-30. doi: 10.1016/j.bbapap.2012.05.009. Epub 2012 Jun 1. Biochim Biophys Acta. 2012. PMID: 22659119

5

Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis.

Filippova EV, Weston LA, Kuhn ML, Geissler B, Gehring AM, Armoush N, Adkins CT, Minasov G, Dubrovska I, Shuvalova L, Winsor JR, Lavis LD, Satchell KJ, Becker DP, Anderson WF, Johnson RJ. Filippova EV, et al. Among authors: johnson rj. J Biol Chem. 2013 Apr 12;288(15):10522-35. doi: 10.1074/jbc.M112.446625. Epub 2013 Feb 19. J Biol Chem. 2013. PMID: 23430251 Free PMC article.

6

Decoupled roles for the atypical, bifurcated binding pocket of the ybfF hydrolase.

Ellis EE, Adkins CT, Galovska NM, Lavis LD, Johnson RJ. Ellis EE, et al. Among authors: johnson rj. Chembiochem. 2013 Jun 17;14(9):1134-44. doi: 10.1002/cbic.201300085. Epub 2013 May 13. Chembiochem. 2013. PMID: 23670977

7

Distinct substrate selectivity of a metabolic hydrolase from Mycobacterium tuberculosis.

Lukowski JK, Savas CP, Gehring AM, McKary MG, Adkins CT, Lavis LD, Hoops GC, Johnson RJ. Lukowski JK, et al. Among authors: johnson rj. Biochemistry. 2014 Dec 2;53(47):7386-95. doi: 10.1021/bi501108u. Epub 2014 Nov 17. Biochemistry. 2014. PMID: 25354081

8

Implementation of a Collaborative Series of Classroom-Based Undergraduate Research Experiences Spanning Chemical Biology, Biochemistry, and Neurobiology.

Kowalski JR, Hoops GC, Johnson RJ. Kowalski JR, et al. Among authors: johnson rj. CBE Life Sci Educ. 2016 winter;15(4):ar55. doi: 10.1187/cbe.16-02-0089. CBE Life Sci Educ. 2016. PMID: 27810870 Free PMC article.

9

In Vivo Delivery and Activation of Masked Fluorogenic Hydrolase Substrates by Endogenous Hydrolases in C. elegans.

Dube S, Dube H, Green NB, Larsen EM, White A, Johnson RJ, Kowalski JR. Dube S, et al. Among authors: johnson rj. Chembiochem. 2017 Sep 19;18(18):1807-1813. doi: 10.1002/cbic.201700278. Epub 2017 Aug 7. Chembiochem. 2017. PMID: 28703362 Free PMC article.

10

Ester-prodrugs of ethambutol control its antibacterial activity and provide rapid screening for mycobacterial hydrolase activity.

Larsen EM, Stephens DC, Clarke NH, Johnson RJ. Larsen EM, et al. Among authors: johnson rj. Bioorg Med Chem Lett. 2017 Oct 1;27(19):4544-4547. doi: 10.1016/j.bmcl.2017.08.057. Epub 2017 Aug 30. Bioorg Med Chem Lett. 2017. PMID: 28882482 Free PMC article.

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