Diem MD - Search Results

1

"Stapling" scFv for multispecific biotherapeutics of superior properties.

Boucher LE, Prinslow EG, Feldkamp M, Yi F, Nanjunda R, Wu SJ, Liu T, Lacy ER, Jacobs S, Kozlyuk N, Del Rosario B, Wu B, Aquino P, Davidson RC, Heyne S, Mazzanti N, Testa J, Diem MD, Gorre E, Mahan A, Nanda H, Gunawardena HP, Gervais A, Armstrong AA, Teplyakov A, Huang C, Zwolak A, Chowdhury P, Cheung WC, Luo J. Boucher LE, et al. Among authors: diem md. MAbs. 2023 Jan-Dec;15(1):2195517. doi: 10.1080/19420862.2023.2195517. MAbs. 2023. PMID: 37074212 Free PMC article.

2

High-Throughput Generation of Bipod (Fab × scFv) Bispecific Antibodies Exploits Differential Chain Expression and Affinity Capture.

Nesspor TC, Kinealy K, Mazzanti N, Diem MD, Boye K, Hoffman H, Springer C, Sprenkle J, Powers G, Jiang H, La Porte SL, Ganesan R, Singh S, Zwolak A. Nesspor TC, et al. Among authors: diem md. Sci Rep. 2020 May 5;10(1):7557. doi: 10.1038/s41598-020-64536-w. Sci Rep. 2020. PMID: 32372058 Free PMC article.

3

Selection of high-affinity Centyrin FN3 domains from a simple library diversified at a combination of strand and loop positions.

Diem MD, Hyun L, Yi F, Hippensteel R, Kuhar E, Lowenstein C, Swift EJ, O'Neil KT, Jacobs SA. Diem MD, et al. Protein Eng Des Sel. 2014 Oct;27(10):419-29. doi: 10.1093/protein/gzu016. Epub 2014 Apr 30. Protein Eng Des Sel. 2014. PMID: 24786107

4

Specific Y14 domains mediate its nucleo-cytoplasmic shuttling and association with spliced mRNA.

Kataoka N, Diem MD, Yoshida M, Hatai C, Dobashi I, Dreyfuss G, Hagiwara M, Ohno M. Kataoka N, et al. Among authors: diem md. Sci Rep. 2011;1:92. doi: 10.1038/srep00092. Epub 2011 Sep 14. Sci Rep. 2011. PMID: 22355610 Free PMC article.

5

A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis.

Berg MG, Wan L, Younis I, Diem MD, Soo M, Wang C, Dreyfuss G. Berg MG, et al. Among authors: diem md. Mol Cell Biol. 2012 Apr;32(7):1271-83. doi: 10.1128/MCB.05788-11. Epub 2012 Jan 17. Mol Cell Biol. 2012. PMID: 22252314 Free PMC article.

6

Design of novel FN3 domains with high stability by a consensus sequence approach.

Jacobs SA, Diem MD, Luo J, Teplyakov A, Obmolova G, Malia T, Gilliland GL, O'Neil KT. Jacobs SA, et al. Among authors: diem md. Protein Eng Des Sel. 2012 Mar;25(3):107-17. doi: 10.1093/protein/gzr064. Epub 2012 Jan 12. Protein Eng Des Sel. 2012. PMID: 22240293

7

PYM binds the cytoplasmic exon-junction complex and ribosomes to enhance translation of spliced mRNAs.

Diem MD, Chan CC, Younis I, Dreyfuss G. Diem MD, et al. Nat Struct Mol Biol. 2007 Dec;14(12):1173-9. doi: 10.1038/nsmb1321. Epub 2007 Nov 18. Nat Struct Mol Biol. 2007. PMID: 18026120

8

eIF4A3 is a novel component of the exon junction complex.

Chan CC, Dostie J, Diem MD, Feng W, Mann M, Rappsilber J, Dreyfuss G. Chan CC, et al. Among authors: diem md. RNA. 2004 Feb;10(2):200-9. doi: 10.1261/rna.5230104. RNA. 2004. PMID: 14730019 Free PMC article.

9

Structure of the Y14-Magoh core of the exon junction complex.

Lau CK, Diem MD, Dreyfuss G, Van Duyne GD. Lau CK, et al. Among authors: diem md. Curr Biol. 2003 May 27;13(11):933-41. doi: 10.1016/s0960-9822(03)00328-2. Curr Biol. 2003. PMID: 12781131 Free article.

10

Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex.

Kataoka N, Diem MD, Kim VN, Yong J, Dreyfuss G. Kataoka N, et al. Among authors: diem md. EMBO J. 2001 Nov 15;20(22):6424-33. doi: 10.1093/emboj/20.22.6424. EMBO J. 2001. PMID: 11707413 Free PMC article.

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