McIntosh K - Search Results

1

IL-1β stimulates a novel, IKKα -dependent, NIK -independent activation of non-canonical NFκB signalling.

McIntosh K, Khalaf YH, Craig R, West C, McCulloch A, Waghmare A, Lawson C, Chan EYW, Mackay S, Paul A, Plevin R. McIntosh K, et al. Cell Signal. 2023 Jul;107:110684. doi: 10.1016/j.cellsig.2023.110684. Epub 2023 Apr 18. Cell Signal. 2023. PMID: 37080443 Free article.

2

The therapeutic potential of proteinase-activated receptors in arthritis.

McIntosh KA, Plevin R, Ferrell WR, Lockhart JC. McIntosh KA, et al. Curr Opin Pharmacol. 2007 Jun;7(3):334-8. doi: 10.1016/j.coph.2007.01.002. Epub 2007 Mar 21. Curr Opin Pharmacol. 2007. PMID: 17369094 Review.

3

Proteinase-activated receptor-2 mediated inhibition of TNFalpha-stimulated JNK activation - A novel paradigm for G(q/11) linked GPCRs.

McIntosh K, Cunningham MR, Cadalbert L, Lockhart J, Boyd G, Ferrell WR, Plevin R. McIntosh K, et al. Cell Signal. 2010 Feb;22(2):265-73. doi: 10.1016/j.cellsig.2009.09.028. Epub 2009 Sep 23. Cell Signal. 2010. PMID: 19781631 Free PMC article.

4

Inhibitory kappa B Kinases as targets for pharmacological regulation.

Gamble C, McIntosh K, Scott R, Ho KH, Plevin R, Paul A. Gamble C, et al. Among authors: mcintosh k. Br J Pharmacol. 2012 Feb;165(4):802-19. doi: 10.1111/j.1476-5381.2011.01608.x. Br J Pharmacol. 2012. PMID: 21797846 Free PMC article. Review.

5

Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4).

Cunningham MR, McIntosh KA, Pediani JD, Robben J, Cooke AE, Nilsson M, Gould GW, Mundell S, Milligan G, Plevin R. Cunningham MR, et al. J Biol Chem. 2012 May 11;287(20):16656-69. doi: 10.1074/jbc.M111.315911. Epub 2012 Mar 12. J Biol Chem. 2012. PMID: 22411985 Free PMC article.

6

Protease-Activated Receptor 2: Are Common Functions in Glial and Immune Cells Linked to Inflammation-Related CNS Disorders?

Bushell TJ, Cunningham MR, McIntosh KA, Moudio S, Plevin R. Bushell TJ, et al. Curr Drug Targets. 2016;17(16):1861-1870. doi: 10.2174/1389450117666151209115232. Curr Drug Targets. 2016. PMID: 26648078 Free article. Review.

7

Proteinase-activated receptors (PARs) as targets for antiplatelet therapy.

Cunningham M, McIntosh K, Bushell T, Sloan G, Plevin R. Cunningham M, et al. Among authors: mcintosh k. Biochem Soc Trans. 2016 Apr 15;44(2):606-12. doi: 10.1042/BST20150282. Biochem Soc Trans. 2016. PMID: 27068977 Free article. Review.

8

Inhibitory Kappa B Kinase α (IKKα) Inhibitors That Recapitulate Their Selectivity in Cells against Isoform-Related Biomarkers.

Anthony NG, Baiget J, Berretta G, Boyd M, Breen D, Edwards J, Gamble C, Gray AI, Harvey AL, Hatziieremia S, Ho KH, Huggan JK, Lang S, Llona-Minguez S, Luo JL, McIntosh K, Paul A, Plevin RJ, Robertson MN, Scott R, Suckling CJ, Sutcliffe OB, Young LC, Mackay SP. Anthony NG, et al. Among authors: mcintosh k. J Med Chem. 2017 Aug 24;60(16):7043-7066. doi: 10.1021/acs.jmedchem.7b00484. Epub 2017 Aug 15. J Med Chem. 2017. PMID: 28737909 Free PMC article.

9

Inhibition of cytokine-mediated JNK signalling by purinergic P2Y₁₁ receptors, a novel protective mechanism in endothelial cells.

Ng PY, McIntosh KA, Hargrave G, Ho KH, Paul A, Plevin R. Ng PY, et al. Cell Signal. 2018 Nov;51:59-71. doi: 10.1016/j.cellsig.2018.07.016. Epub 2018 Aug 2. Cell Signal. 2018. PMID: 30076967 Free article.

10

Novel protective role for MAP kinase phosphatase 2 in inflammatory arthritis.

Schroeder J, Ross K, McIntosh K, Jabber S, Woods S, Crowe J, Patterson Kane J, Alexander J, Lawrence C, Plevin R. Schroeder J, et al. Among authors: mcintosh k. RMD Open. 2019 Jan 11;5(1):e000711. doi: 10.1136/rmdopen-2018-000711. eCollection 2019. RMD Open. 2019. PMID: 30713718 Free PMC article.

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