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Page 1
Prior metabolite extraction fully preserves RNAseq quality and enables integrative multi-'omics analysis of the liver metabolic response to viral infection.
Madaj ZB, Dahabieh MS, Kamalumpundi V, Muhire B, Pettinga J, Siwicki RA, Ellis AE, Isaguirre C, Escobar Galvis ML, DeCamp L, Jones RG, Givan SA, Adams M, Sheldon RD. Madaj ZB, et al. Among authors: dahabieh ms. RNA Biol. 2023 Jan;20(1):186-197. doi: 10.1080/15476286.2023.2204586. RNA Biol. 2023. PMID: 37095747 Free PMC article.
Carbon source availability drives nutrient utilization in CD8+ T cells.
Kaymak I, Luda KM, Duimstra LR, Ma EH, Longo J, Dahabieh MS, Faubert B, Oswald BM, Watson MJ, Kitchen-Goosen SM, DeCamp LM, Compton SE, Fu Z, DeBerardinis RJ, Williams KS, Sheldon RD, Jones RG. Kaymak I, et al. Among authors: dahabieh ms. Cell Metab. 2022 Sep 6;34(9):1298-1311.e6. doi: 10.1016/j.cmet.2022.07.012. Epub 2022 Aug 17. Cell Metab. 2022. PMID: 35981545 Free PMC article.
13C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8+ T cells.
Ma EH, Dahabieh MS, DeCamp LM, Kaymak I, Kitchen-Goosen SM, Roy DG, Verway MJ, Johnson RM, Samborska B, Scullion CA, Steadman M, Vos M, Roddy TP, Krawczyk CM, Williams KS, Sheldon RD, Jones RG. Ma EH, et al. Among authors: dahabieh ms. bioRxiv [Preprint]. 2023 Jun 11:2023.06.09.544407. doi: 10.1101/2023.06.09.544407. bioRxiv. 2023. Update in: Sci Adv. 2024 May 31;10(22):eadj1431. doi: 10.1126/sciadv.adj1431 PMID: 37333111 Free PMC article. Updated. Preprint.
Ketolysis drives CD8+ T cell effector function through effects on histone acetylation.
Luda KM, Longo J, Kitchen-Goosen SM, Duimstra LR, Ma EH, Watson MJ, Oswald BM, Fu Z, Madaj Z, Kupai A, Dickson BM, DeCamp LM, Dahabieh MS, Compton SE, Teis R, Kaymak I, Lau KH, Kelly DP, Puchalska P, Williams KS, Krawczyk CM, Lévesque D, Boisvert FM, Sheldon RD, Rothbart SB, Crawford PA, Jones RG. Luda KM, et al. Among authors: dahabieh ms. Immunity. 2023 Sep 12;56(9):2021-2035.e8. doi: 10.1016/j.immuni.2023.07.002. Epub 2023 Jul 28. Immunity. 2023. PMID: 37516105 Free PMC article.
13C metabolite tracing reveals glutamine and acetate as critical in vivo fuels for CD8 T cells.
Ma EH, Dahabieh MS, DeCamp LM, Kaymak I, Kitchen-Goosen SM, Oswald BM, Longo J, Roy DG, Verway MJ, Johnson RM, Samborska B, Duimstra LR, Scullion CA, Steadman M, Vos M, Roddy TP, Krawczyk CM, Williams KS, Sheldon RD, Jones RG. Ma EH, et al. Among authors: dahabieh ms. Sci Adv. 2024 May 31;10(22):eadj1431. doi: 10.1126/sciadv.adj1431. Epub 2024 May 29. Sci Adv. 2024. PMID: 38809979 Free PMC article.
NRF2-dependent regulation of the prostacyclin receptor PTGIR drives CD8 T cell exhaustion.
Dahabieh MS, DeCamp LM, Oswald BM, Kitchen-Goosen SM, Fu Z, Vos M, Compton SE, Longo J, Williams KS, Ellis AE, Johnson A, Sodiya I, Vincent M, Lee H, Sheldon RD, Krawczyk CM, Yao C, Wu T, Jones RG. Dahabieh MS, et al. bioRxiv [Preprint]. 2024 Jun 28:2024.06.23.600279. doi: 10.1101/2024.06.23.600279. bioRxiv. 2024. PMID: 38979360 Free PMC article. Preprint.
Nutrient-driven histone code determines exhausted CD8+ T cell fates.
Ma S, Dahabieh MS, Mann TH, Zhao S, McDonald B, Song WS, Chung HK, Farsakoglu Y, Garcia-Rivera L, Hoffmann FA, Xu S, Du VY, Chen D, Furgiuele J, LaPorta M, Jacobs E, DeCamp LM, Oswald BM, Sheldon RD, Ellis AE, Liu L, He P, Wang Y, Jang C, Jones RG, Kaech SM. Ma S, et al. Among authors: dahabieh ms. Science. 2024 Dec 12:eadj3020. doi: 10.1126/science.adj3020. Online ahead of print. Science. 2024. PMID: 39666821
Dietary Restriction Enhances CD8+ T Cell Ketolysis to Limit Exhaustion and Boost Anti-Tumor Immunity.
Oswald BM, DeCamp LM, Longo J, Dahabieh MS, Bunda N, Ma S, Watson MJ, Sheldon RD, Vincent MP, Johnson BK, Ellis AE, Soper-Hopper MT, Isaguirre CN, Shen H, Williams KS, Crawford PA, Kaech S, Jang HJ, Krawczyk CM, Jones RG. Oswald BM, et al. Among authors: dahabieh ms. bioRxiv [Preprint]. 2024 Nov 15:2024.11.14.621733. doi: 10.1101/2024.11.14.621733. bioRxiv. 2024. PMID: 39605550 Free PMC article. Preprint.
Glucose-dependent glycosphingolipid biosynthesis fuels CD8+ T cell function and tumor control.
Longo J, DeCamp LM, Oswald BM, Teis R, Reyes-Oliveras A, Dahabieh MS, Ellis AE, Vincent MP, Damico H, Gallik KL, Compton SE, Capan CD, Williams KS, Esquibel CR, Madaj ZB, Lee H, Roy DG, Krawczyk CM, Haab BB, Sheldon RD, Jones RG. Longo J, et al. Among authors: dahabieh ms. bioRxiv [Preprint]. 2024 Oct 14:2024.10.10.617261. doi: 10.1101/2024.10.10.617261. bioRxiv. 2024. PMID: 39464161 Free PMC article. Preprint.
Blocking tumor-intrinsic MNK1 kinase restricts metabolic adaptation and diminishes liver metastasis.
Preston SEJ, Dahabieh MS, Flores González RE, Gonçalves C, Richard VR, Leibovitch M, Dakin E, Papadopoulos T, Lopez Naranjo C, McCallum PA, Huang F, Gagnon N, Perrino S, Zahedi RP, Borchers CH, Jones RG, Brodt P, Miller WH Jr, Del Rincón SV. Preston SEJ, et al. Among authors: dahabieh ms. Sci Adv. 2024 Sep 13;10(37):eadi7673. doi: 10.1126/sciadv.adi7673. Epub 2024 Sep 13. Sci Adv. 2024. PMID: 39270021 Free PMC article.
31 results