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207 results

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Page 1
Senescent T cells: Beneficial and detrimental roles.
Laphanuwat P, Gomes DCO, Akbar AN. Laphanuwat P, et al. Among authors: akbar an. Immunol Rev. 2023 Jul;316(1):160-175. doi: 10.1111/imr.13206. Epub 2023 Apr 25. Immunol Rev. 2023. PMID: 37098109 Free PMC article. Review.
Lesional senescent CD4+ T cells mediate bystander cytolysis and contribute to the skin pathology of human cutaneous leishmaniasis.
Covre LP, Fantecelle CH, Garcia de Moura R, Oliveira Lopes P, Sarmento IV, Freire-de-Lima CG, Decote-Ricardo D, de Matos Guedes HL, da Fonsceca-Martins AM, de Carvalho LP, de Carvalho EM, Mosser DM, Falqueto A, Akbar AN, Gomes DCO. Covre LP, et al. Among authors: akbar an. Front Immunol. 2024 Oct 21;15:1475146. doi: 10.3389/fimmu.2024.1475146. eCollection 2024. Front Immunol. 2024. PMID: 39497830 Free PMC article.
Clearance of senescent macrophages ameliorates tumorigenesis in KRAS-driven lung cancer.
Haston S, Gonzalez-Gualda E, Morsli S, Ge J, Reen V, Calderwood A, Moutsopoulos I, Panousopoulos L, Deletic P, Carreno G, Guiho R, Manshaei S, Gonzalez-Meljem JM, Lim HY, Simpson DJ, Birch J, Pallikonda HA, Chandra T, Macias D, Doherty GJ, Rassl DM, Rintoul RC, Signore M, Mohorianu I, Akbar AN, Gil J, Muñoz-Espín D, Martinez-Barbera JP. Haston S, et al. Among authors: akbar an. Cancer Cell. 2023 Jul 10;41(7):1242-1260.e6. doi: 10.1016/j.ccell.2023.05.004. Epub 2023 Jun 1. Cancer Cell. 2023. PMID: 37267953 Free article.
Senescence-related genes are associated with the immunopathology signature of American Tegumentary Leishmaniasis lesions and may predict progression to mucosal leishmaniasis.
Fantecelle CH, Polaco Covre L, Lopes PO, Sarmento IV, Decote-Ricardo D, Geraldo Freire de Lima C, de Matos Guedes HL, Pimentel MIF, Conceição-Silva F, Maretti-Mira AC, Borges VM, Pedreira de Carvalho L, de Carvalho EM, Mosser D, Falqueto A, Akbar AN, Gomes DCO. Fantecelle CH, et al. Among authors: akbar an. Clin Exp Immunol. 2024 Oct 21:uxae088. doi: 10.1093/cei/uxae088. Online ahead of print. Clin Exp Immunol. 2024. PMID: 39428748
Upregulation of keratin 15 is required for varicella-zoster virus replication in keratinocytes and is attenuated in the live attenuated vOka vaccine strain.
Tommasi C, Yogev O, Yee MB, Drousioti A, Jones M, Ring A, Singh M, Dry I, Atkins O, Naeem AS, Kriplani N, Akbar AN, Haas JG, O'Toole EA, Kinchington PR, Breuer J. Tommasi C, et al. Among authors: akbar an. Virol J. 2024 Oct 9;21(1):253. doi: 10.1186/s12985-024-02514-8. Virol J. 2024. PMID: 39385182 Free PMC article.
Post-resolution macrophages shape long-term tissue immunity and integrity in a mouse model of pneumococcal pneumonia.
Feehan KT, Bridgewater HE, Stenkiewicz-Witeska J, De Maeyer RPH, Ferguson J, Mack M, Brown J, Ercoli G, Mawer CM, Akbar AN, Glanville JRW, Jalali P, Bracken OV, Nicolaou A, Kendall AC, Sugimoto MA, Gilroy DW. Feehan KT, et al. Among authors: akbar an. Nat Commun. 2024 May 21;15(1):4326. doi: 10.1038/s41467-024-48138-y. Nat Commun. 2024. PMID: 38773113 Free PMC article.
207 results