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Page 1
Mesoscale DNA feature in antibody-coding sequence facilitates somatic hypermutation.
Wang Y, Zhang S, Yang X, Hwang JK, Zhan C, Lian C, Wang C, Gui T, Wang B, Xie X, Dai P, Zhang L, Tian Y, Zhang H, Han C, Cai Y, Hao Q, Ye X, Liu X, Liu J, Cao Z, Huang S, Song J, Pan-Hammarström Q, Zhao Y, Alt FW, Zheng X, Da LT, Yeap LS, Meng FL. Wang Y, et al. Among authors: yeap ls. Cell. 2023 May 11;186(10):2193-2207.e19. doi: 10.1016/j.cell.2023.03.030. Epub 2023 Apr 24. Cell. 2023. PMID: 37098343 Free article.
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.
Compagno M, Wang Q, Pighi C, Cheong TC, Meng FL, Poggio T, Yeap LS, Karaca E, Blasco RB, Langellotto F, Ambrogio C, Voena C, Wiestner A, Kasar SN, Brown JR, Sun J, Wu CJ, Gostissa M, Alt FW, Chiarle R. Compagno M, et al. Among authors: yeap ls. Nature. 2017 Feb 23;542(7642):489-493. doi: 10.1038/nature21406. Epub 2017 Feb 15. Nature. 2017. PMID: 28199309 Free PMC article.
Sequence intrinsic somatic mutation mechanisms contribute to affinity maturation of VRC01-class HIV-1 broadly neutralizing antibodies.
Hwang JK, Wang C, Du Z, Meyers RM, Kepler TB, Neuberg D, Kwong PD, Mascola JR, Joyce MG, Bonsignori M, Haynes BF, Yeap LS, Alt FW. Hwang JK, et al. Among authors: yeap ls. Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):8614-8619. doi: 10.1073/pnas.1709203114. Epub 2017 Jul 26. Proc Natl Acad Sci U S A. 2017. PMID: 28747530 Free PMC article.
ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells.
Liu X, Liu T, Shang Y, Dai P, Zhang W, Lee BJ, Huang M, Yang D, Wu Q, Liu LD, Zheng X, Zhou BO, Dong J, Yeap LS, Hu J, Xiao T, Zha S, Casellas R, Liu XS, Meng FL. Liu X, et al. Among authors: yeap ls. Cell Res. 2020 Sep;30(9):732-744. doi: 10.1038/s41422-020-0328-3. Epub 2020 Apr 30. Cell Res. 2020. PMID: 32355287 Free PMC article.
REV7 is required for processing AID initiated DNA lesions in activated B cells.
Yang D, Sun Y, Chen J, Zhang Y, Fan S, Huang M, Xie X, Cai Y, Shang Y, Gui T, Sun L, Hu J, Dong J, Yeap LS, Wang X, Xiao W, Meng FL. Yang D, et al. Among authors: yeap ls. Nat Commun. 2020 Jun 4;11(1):2812. doi: 10.1038/s41467-020-16632-8. Nat Commun. 2020. PMID: 32499490 Free PMC article.
22 results