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547 results

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Page 1
SRSF2-P95H decreases JAK/STAT signaling in hematopoietic cells and delays myelofibrosis development in mice.
Willekens C, Laplane L, Dagher T, Benlabiod C, Papadopoulos N, Lacout C, Rameau P, Catelain C, Alfaro A, Edmond V, Signolle N, Marchand V, Droin N, Hoogenboezem R, Schneider RK, Penson A, Abdel-Wahab O, Giraudier S, Pasquier F, Marty C, Plo I, Villeval JL, Constantinescu SN, Porteu F, Vainchenker W, Solary E. Willekens C, et al. Among authors: vainchenker w. Leukemia. 2023 Jun;37(6):1287-1297. doi: 10.1038/s41375-023-01878-0. Epub 2023 Apr 26. Leukemia. 2023. PMID: 37100881
Recent advances in therapies for primary myelofibrosis.
Vainchenker W, Yahmi N, Havelange V, Marty C, Plo I, Constantinescu SN. Vainchenker W, et al. Fac Rev. 2023 Sep 26;12:23. doi: 10.12703/r/12-23. eCollection 2023. Fac Rev. 2023. PMID: 37771602 Free PMC article. Review.
Comparative clinical and molecular landscape of primary and secondary myelofibrosis: Superior performance of MIPSS70+ v2.0 over MYSEC-PM.
Guerra M, Pasquer H, Daltro de Oliveira R, Soret-Dulphy J, Maslah N, Zhao LP, Marcault C, Cazaux M, Gauthier N, Verger E, Parquet N, Vainchenker W, Raffoux E, Giraudier S, Cassinat B, Kiladjian JJ, Benajiba L. Guerra M, et al. Among authors: vainchenker w. Am J Hematol. 2024 Apr;99(4):741-744. doi: 10.1002/ajh.27226. Epub 2024 Jan 26. Am J Hematol. 2024. PMID: 38279562
Monocytes generated by interleukin-6-treated human hematopoietic stem and progenitor cells secrete calprotectin that inhibits erythropoiesis.
Marchand V, Laplane L, Valensi L, Plo I, Aglave M, Silvin A, Pasquier F, Porteu F, Vainchenker W, Selimoglu-Buet D, Droin N, Raslova H, Marcel V, Diaz JJ, Fontenay M, Solary E. Marchand V, et al. Among authors: vainchenker w. iScience. 2024 Dec 2;28(1):111522. doi: 10.1016/j.isci.2024.111522. eCollection 2025 Jan 17. iScience. 2024. PMID: 39811665 Free PMC article.
Selective targeting of mutated calreticulin by the monoclonal antibody INCA033989 inhibits oncogenic function of MPN.
Reis ES, Buonpane R, Celik H, Marty C, Lei A, Jobe F, Rupar M, Zhang Y, DiMatteo D, Awdew R, Ferreira BL, Leffet L, Lu L, Rosa E, Evrard M, Trivedi G, Wass B, Horsey A, He X, Covington M, Volgina A, Pasquier F, Legros L, Fouquet G, Vainchenker W, Yang YO, Barker B, Zhou J, Stewart S, Hitchcock IS, Dhanak D, Macarron R, Plo I, Nastri H, Mayes PA. Reis ES, et al. Among authors: vainchenker w. Blood. 2024 Nov 28;144(22):2336-2348. doi: 10.1182/blood.2024024373. Blood. 2024. PMID: 39255409 Free article.
DNMT3A gates IFN-induced MPN HSC exhaustion.
Constantinescu SN, Vainchenker W. Constantinescu SN, et al. Among authors: vainchenker w. Blood. 2024 Jun 13;143(24):2445-2446. doi: 10.1182/blood.2024024448. Blood. 2024. PMID: 38869916 No abstract available.
Deregulation of the p19/CDK4/CDK6 axis in Jak2V617F megakaryocytes accelerates the development of myelofibrosis.
Duparc H, Muller D, Gilles L, Chédeville AL, El Khoury M, Guignard R, Debili N, Wittner M, Kauskot A, Pasquier F, Antony-Debré I, Marty C, Vainchenker W, Plo I, Raslova H. Duparc H, et al. Among authors: vainchenker w. Leukemia. 2024 Apr;38(4):898-902. doi: 10.1038/s41375-024-02170-5. Epub 2024 Feb 20. Leukemia. 2024. PMID: 38378843 No abstract available.
Distinct clinico-molecular arterial and venous thrombosis scores for myeloproliferative neoplasms risk stratification.
Pasquer H, Daltro de Oliveira R, Vasseur L, Soret-Dulphy J, Maslah N, Zhao LP, Marcault C, Cazaux M, Gauthier N, Verger E, Parquet N, Vainchenker W, Raffoux E, Ugo V, Luque Paz D, Roy L, Lambert WC, Ianotto JC, Lippert E, Giraudier S, Cassinat B, Kiladjian JJ, Benajiba L. Pasquer H, et al. Among authors: vainchenker w. Leukemia. 2024 Feb;38(2):326-339. doi: 10.1038/s41375-023-02114-5. Epub 2023 Dec 27. Leukemia. 2024. PMID: 38148396
547 results