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TLR Agonist Therapy of Metastatic Breast Cancer in Mice.
Klinman DM, Goguet E, Tross D. Klinman DM, et al. J Immunother. 2023 Jun 1;46(5):170-177. doi: 10.1097/CJI.0000000000000467. Epub 2023 Apr 28. J Immunother. 2023. PMID: 37103328 Free PMC article.
Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1β axes bridge innate immunity and epithelial apoptosis to promote emphysema.
Ruwanpura SM, McLeod L, Dousha LF, Seow HJ, West AC, West AJ, Weng T, Alanazi M, MacDonald M, King PT, Bardin PG, Gabay C, Klinman DM, Bozinovski S, Vlahos R, Anderson GP, Rose-John S, Saad MI, Jenkins BJ. Ruwanpura SM, et al. Among authors: klinman dm. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2201494119. doi: 10.1073/pnas.2201494119. Epub 2022 Aug 29. Proc Natl Acad Sci U S A. 2022. PMID: 36037355 Free PMC article.
STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis.
Dawson RE, Deswaerte V, West AC, Tang K, West AJ, Balic JJ, Gearing LJ, Saad MI, Yu L, Wu Y, Bhathal PS, Kumar B, Chakrabarti JT, Zavros Y, Oshima H, Klinman DM, Oshima M, Tan P, Jenkins BJ. Dawson RE, et al. Among authors: klinman dm. Gut. 2022 Aug;71(8):1515-1531. doi: 10.1136/gutjnl-2020-323916. Epub 2021 Sep 6. Gut. 2022. PMID: 34489308
CpG Oligonucleotides as Vaccine Adjuvants.
Kayraklioglu N, Horuluoglu B, Klinman DM. Kayraklioglu N, et al. Among authors: klinman dm. Methods Mol Biol. 2021;2197:51-85. doi: 10.1007/978-1-0716-0872-2_4. Methods Mol Biol. 2021. PMID: 32827132 Review.
Immunotherapy in sepsis - brake or accelerate?
Steinhagen F, Schmidt SV, Schewe JC, Peukert K, Klinman DM, Bode C. Steinhagen F, et al. Among authors: klinman dm. Pharmacol Ther. 2020 Apr;208:107476. doi: 10.1016/j.pharmthera.2020.107476. Epub 2020 Jan 10. Pharmacol Ther. 2020. PMID: 31931100 Free article. Review.
283 results