Blackburn NJ - Search Results

1

Peptide Selenocysteine Substitutions Reveal Direct Substrate-Enzyme Interactions at Auxiliary Clusters in Radical S-Adenosyl-l-methionine Maturases.

Rush KW, Eastman KAS, Kincannon WM, Blackburn NJ, Bandarian V. Rush KW, et al. Among authors: blackburn nj. J Am Chem Soc. 2023 May 10;145(18):10167-10177. doi: 10.1021/jacs.3c00831. Epub 2023 Apr 27. J Am Chem Soc. 2023. PMID: 37104670 Free PMC article.

2

Copper monooxygenase reactivity: Do consensus mechanisms accurately reflect experimental observations?

Welch EF, Rush KW, Arias RJ, Blackburn NJ. Welch EF, et al. Among authors: blackburn nj. J Inorg Biochem. 2022 Jun;231:111780. doi: 10.1016/j.jinorgbio.2022.111780. Epub 2022 Feb 28. J Inorg Biochem. 2022. PMID: 35303611 Free PMC article.

3

Pre-Steady-State Reactivity of Peptidylglycine Monooxygenase Implicates Ascorbate in Substrate Triggering of the Active Conformer.

Welch EF, Rush KW, Arias RJ, Blackburn NJ. Welch EF, et al. Among authors: blackburn nj. Biochemistry. 2022 Apr 19;61(8):665-677. doi: 10.1021/acs.biochem.2c00080. Epub 2022 Apr 5. Biochemistry. 2022. PMID: 35380039 Free PMC article.

4

Capturing the Binuclear Copper State of Peptidylglycine Monooxygenase Using a Peptidyl-Homocysteine Lure.

Rush KW, Eastman KAS, Welch EF, Bandarian V, Blackburn NJ. Rush KW, et al. Among authors: blackburn nj. J Am Chem Soc. 2024 Feb 28;146(8):5074-5080. doi: 10.1021/jacs.3c14705. Epub 2024 Feb 16. J Am Chem Soc. 2024. PMID: 38363651

5

Mechanisms of Copper Selectivity and Release by the Metallochaperone CusF: Insights from CO-Binding, Rapid-Freeze-Quench EXAFS, and Unnatural Amino Acid Substitution.

Rush KW, Alwan KB, Conner AT, Welch EF, Blackburn NJ. Rush KW, et al. Among authors: blackburn nj. Inorg Chem. 2024 Nov 11;63(45):21519-21530. doi: 10.1021/acs.inorgchem.4c03578. Epub 2024 Oct 29. Inorg Chem. 2024. PMID: 39472424

6

Anatomy of a red copper center: spectroscopic identification and reactivity of the copper centers of Bacillus subtilis Sco and its Cys-to-Ala variants.

Siluvai GS, Mayfield M, Nilges MJ, Debeer George S, Blackburn NJ. Siluvai GS, et al. Among authors: blackburn nj. J Am Chem Soc. 2010 Apr 14;132(14):5215-26. doi: 10.1021/ja910759v. J Am Chem Soc. 2010. PMID: 20232870 Free PMC article.

7

Lumenal loop M672-P707 of the Menkes protein (ATP7A) transfers copper to peptidylglycine monooxygenase.

Otoikhian A, Barry AN, Mayfield M, Nilges M, Huang Y, Lutsenko S, Blackburn NJ. Otoikhian A, et al. Among authors: blackburn nj. J Am Chem Soc. 2012 Jun 27;134(25):10458-68. doi: 10.1021/ja301221s. Epub 2012 Jun 13. J Am Chem Soc. 2012. PMID: 22577880 Free PMC article.

8

Stable Cu(II) and Cu(I) mononuclear intermediates in the assembly of the CuA center of Thermus thermophilus cytochrome oxidase.

Chacón KN, Blackburn NJ. Chacón KN, et al. Among authors: blackburn nj. J Am Chem Soc. 2012 Oct 3;134(39):16401-12. doi: 10.1021/ja307276z. Epub 2012 Sep 19. J Am Chem Soc. 2012. PMID: 22946616 Free PMC article.

9

Copper-peptide complex structure and reactivity when found in conserved His-X(aa)-His sequences.

Park GY, Lee JY, Himes RA, Thomas GS, Blackburn NJ, Karlin KD. Park GY, et al. Among authors: blackburn nj. J Am Chem Soc. 2014 Sep 10;136(36):12532-5. doi: 10.1021/ja505098v. Epub 2014 Aug 29. J Am Chem Soc. 2014. PMID: 25171435 Free PMC article.

10

Incorporation of Ni²⁺, Co²⁺, and Selenocysteine into the Auxiliary Fe-S Cluster of the Radical SAM Enzyme HydG.

Rao G, Alwan KB, Blackburn NJ, Britt RD. Rao G, et al. Among authors: blackburn nj. Inorg Chem. 2019 Oct 7;58(19):12601-12608. doi: 10.1021/acs.inorgchem.9b01293. Epub 2019 Sep 20. Inorg Chem. 2019. PMID: 31539235 Free PMC article.

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