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The origins and functions of hepatic polyploidy.
Zhang S, Lin YH, Tarlow B, Zhu H. Zhang S, et al. Among authors: lin yh. Cell Cycle. 2019 Jun;18(12):1302-1315. doi: 10.1080/15384101.2019.1618123. Epub 2019 May 26. Cell Cycle. 2019. PMID: 31096847 Free PMC article. Review.
Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.
Lin YH, Zhang S, Zhu M, Lu T, Chen K, Wen Z, Wang S, Xiao G, Luo D, Jia Y, Li L, MacConmara M, Hoshida Y, Singal AG, Yopp A, Wang T, Zhu H. Lin YH, et al. Gastroenterology. 2020 May;158(6):1698-1712.e14. doi: 10.1053/j.gastro.2020.01.026. Epub 2020 Jan 20. Gastroenterology. 2020. PMID: 31972235 Free PMC article.
Liver homeostasis is maintained by midlobular zone 2 hepatocytes.
Wei Y, Wang YG, Jia Y, Li L, Yoon J, Zhang S, Wang Z, Zhang Y, Zhu M, Sharma T, Lin YH, Hsieh MH, Albrecht JH, Le PT, Rosen CJ, Wang T, Zhu H. Wei Y, et al. Among authors: lin yh. Science. 2021 Feb 26;371(6532):eabb1625. doi: 10.1126/science.abb1625. Science. 2021. PMID: 33632817 Free PMC article.
Genetic and Cellular Contributions to Liver Regeneration.
Liang R, Lin YH, Zhu H. Liang R, et al. Among authors: lin yh. Cold Spring Harb Perspect Biol. 2021 Nov 8;14(9):a040832. doi: 10.1101/cshperspect.a040832. Online ahead of print. Cold Spring Harb Perspect Biol. 2021. PMID: 34750173 Free PMC article.
Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease.
Wang Z, Zhu S, Jia Y, Wang Y, Kubota N, Fujiwara N, Gordillo R, Lewis C, Zhu M, Sharma T, Li L, Zeng Q, Lin YH, Hsieh MH, Gopal P, Wang T, Hoare M, Campbell P, Hoshida Y, Zhu H. Wang Z, et al. Among authors: lin yh. bioRxiv [Preprint]. 2023 Mar 21:2023.03.20.533505. doi: 10.1101/2023.03.20.533505. bioRxiv. 2023. Update in: Cell. 2023 Apr 27;186(9):1968-1984.e20. doi: 10.1016/j.cell.2023.03.014 PMID: 36993727 Free PMC article. Updated. Preprint.
3,867 results