Garcia NK - Search Results

1

Structural dynamics reveal subtype-specific activation and inhibition of influenza virus hemagglutinin.

Garcia NK, Kephart SM, Benhaim MA, Matsui T, Mileant A, Guttman M, Lee KK. Garcia NK, et al. J Biol Chem. 2023 Jun;299(6):104765. doi: 10.1016/j.jbc.2023.104765. Epub 2023 Apr 28. J Biol Chem. 2023. PMID: 37121546 Free PMC article.

2

Dynamic changes during acid-induced activation of influenza hemagglutinin.

Garcia NK, Guttman M, Ebner JL, Lee KK. Garcia NK, et al. Structure. 2015 Apr 7;23(4):665-76. doi: 10.1016/j.str.2015.02.006. Epub 2015 Mar 12. Structure. 2015. PMID: 25773144 Free PMC article.

3

Solution structure, conformational dynamics, and CD4-induced activation in full-length, glycosylated, monomeric HIV gp120.

Guttman M, Kahn M, Garcia NK, Hu SL, Lee KK. Guttman M, et al. Among authors: garcia nk. J Virol. 2012 Aug;86(16):8750-64. doi: 10.1128/JVI.07224-11. Epub 2012 Jun 6. J Virol. 2012. PMID: 22674993 Free PMC article.

4

CD4-induced activation in a soluble HIV-1 Env trimer.

Guttman M, Garcia NK, Cupo A, Matsui T, Julien JP, Sanders RW, Wilson IA, Moore JP, Lee KK. Guttman M, et al. Among authors: garcia nk. Structure. 2014 Jul 8;22(7):974-84. doi: 10.1016/j.str.2014.05.001. Epub 2014 Jun 12. Structure. 2014. PMID: 24931470 Free PMC article.

5

Dynamic Viral Glycoprotein Machines: Approaches for Probing Transient States That Drive Membrane Fusion.

Garcia NK, Lee KK. Garcia NK, et al. Viruses. 2016 Jan 11;8(1):15. doi: 10.3390/v8010015. Viruses. 2016. PMID: 26761026 Free PMC article. Review.

6

Structural monitoring of a transient intermediate in the hemagglutinin fusion machinery on influenza virions.

Benhaim MA, Mangala Prasad V, Garcia NK, Guttman M, Lee KK. Benhaim MA, et al. Among authors: garcia nk. Sci Adv. 2020 Apr 29;6(18):eaaz8822. doi: 10.1126/sciadv.aaz8822. eCollection 2020 May. Sci Adv. 2020. PMID: 32494683 Free PMC article.

7

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.

Strauch EM, Bernard SM, La D, Bohn AJ, Lee PS, Anderson CE, Nieusma T, Holstein CA, Garcia NK, Hooper KA, Ravichandran R, Nelson JW, Sheffler W, Bloom JD, Lee KK, Ward AB, Yager P, Fuller DH, Wilson IA, Baker D. Strauch EM, et al. Among authors: garcia nk. Nat Biotechnol. 2017 Jul;35(7):667-671. doi: 10.1038/nbt.3907. Epub 2017 Jun 12. Nat Biotechnol. 2017. PMID: 28604661 Free PMC article.

8

Optimizing Hydroxyl Radical Footprinting Analysis of Biotherapeutics Using Internal Standard Dosimetry.

Garcia NK, Sreedhara A, Deperalta G, Wecksler AT. Garcia NK, et al. J Am Soc Mass Spectrom. 2020 Jul 1;31(7):1563-1571. doi: 10.1021/jasms.0c00146. Epub 2020 May 27. J Am Soc Mass Spectrom. 2020. PMID: 32407079

9

Current Trends in Biotherapeutic Higher Order Structure Characterization by Irreversible Covalent Footprinting Mass Spectrometry.

Garcia NK, Deperalta G, Wecksler AT. Garcia NK, et al. Protein Pept Lett. 2019;26(1):35-43. doi: 10.2174/0929866526666181128141953. Protein Pept Lett. 2019. PMID: 30484396 Review.

10

Structural basis for dual-mode inhibition of the ABC transporter MsbA.

Ho H, Miu A, Alexander MK, Garcia NK, Oh A, Zilberleyb I, Reichelt M, Austin CD, Tam C, Shriver S, Hu H, Labadie SS, Liang J, Wang L, Wang J, Lu Y, Purkey HE, Quinn J, Franke Y, Clark K, Beresini MH, Tan MW, Sellers BD, Maurer T, Koehler MFT, Wecksler AT, Kiefer JR, Verma V, Xu Y, Nishiyama M, Payandeh J, Koth CM. Ho H, et al. Among authors: garcia nk. Nature. 2018 May;557(7704):196-201. doi: 10.1038/s41586-018-0083-5. Epub 2018 May 2. Nature. 2018. PMID: 29720648

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