French S - Search Results

1

Inhibiting fatty acid synthesis overcomes colistin resistance.

Carfrae LA, Rachwalski K, French S, Gordzevich R, Seidel L, Tsai CN, Tu MM, MacNair CR, Ovchinnikova OG, Clarke BR, Whitfield C, Brown ED. Carfrae LA, et al. Among authors: french s. Nat Microbiol. 2023 Jun;8(6):1026-1038. doi: 10.1038/s41564-023-01369-z. Epub 2023 May 1. Nat Microbiol. 2023. PMID: 37127701

2

Discovery of novel cell wall-active compounds using P ywaC, a sensitive reporter of cell wall stress, in the model gram-positive bacterium Bacillus subtilis.

Czarny TL, Perri AL, French S, Brown ED. Czarny TL, et al. Among authors: french s. Antimicrob Agents Chemother. 2014 Jun;58(6):3261-9. doi: 10.1128/AAC.02352-14. Epub 2014 Mar 31. Antimicrob Agents Chemother. 2014. PMID: 24687489 Free PMC article.

3

Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase.

Farha MA, Czarny TL, Myers CL, Worrall LJ, French S, Conrady DG, Wang Y, Oldfield E, Strynadka NC, Brown ED. Farha MA, et al. Among authors: french s. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11048-53. doi: 10.1073/pnas.1511751112. Epub 2015 Aug 17. Proc Natl Acad Sci U S A. 2015. PMID: 26283394 Free PMC article.

4

Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins.

King AM, King DT, French S, Brouillette E, Asli A, Alexander JA, Vuckovic M, Maiti SN, Parr TR Jr, Brown ED, Malouin F, Strynadka NC, Wright GD. King AM, et al. Among authors: french s. ACS Chem Biol. 2016 Apr 15;11(4):864-8. doi: 10.1021/acschembio.5b00944. Epub 2016 Jan 14. ACS Chem Biol. 2016. PMID: 26731698

5

A robust platform for chemical genomics in bacterial systems.

French S, Mangat C, Bharat A, Côté JP, Mori H, Brown ED. French S, et al. Mol Biol Cell. 2016 Mar 15;27(6):1015-25. doi: 10.1091/mbc.E15-08-0573. Epub 2016 Jan 20. Mol Biol Cell. 2016. PMID: 26792836 Free PMC article.

6

Assembly and clustering of natural antibiotics guides target identification.

Johnston CW, Skinnider MA, Dejong CA, Rees PN, Chen GM, Walker CG, French S, Brown ED, Bérdy J, Liu DY, Magarvey NA. Johnston CW, et al. Among authors: french s. Nat Chem Biol. 2016 Apr;12(4):233-9. doi: 10.1038/nchembio.2018. Epub 2016 Feb 1. Nat Chem Biol. 2016. PMID: 26829473

7

Cold Stress Makes Escherichia coli Susceptible to Glycopeptide Antibiotics by Altering Outer Membrane Integrity.

Stokes JM, French S, Ovchinnikova OG, Bouwman C, Whitfield C, Brown ED. Stokes JM, et al. Among authors: french s. Cell Chem Biol. 2016 Feb 18;23(2):267-277. doi: 10.1016/j.chembiol.2015.12.011. Epub 2016 Feb 4. Cell Chem Biol. 2016. PMID: 26853624 Free article.

8

A cell-based approach to characterize antimicrobial compounds through kinetic dose response.

MacNair CR, Stokes JM, French S, Myers CL, Iyer KR, Brown ED. MacNair CR, et al. Among authors: french s. Bioorg Med Chem. 2016 Dec 15;24(24):6315-6319. doi: 10.1016/j.bmc.2016.09.053. Epub 2016 Sep 22. Bioorg Med Chem. 2016. PMID: 27713016

9

Identification of Two Phosphate Starvation-induced Wall Teichoic Acid Hydrolases Provides First Insights into the Degradative Pathway of a Key Bacterial Cell Wall Component.

Myers CL, Li FK, Koo BM, El-Halfawy OM, French S, Gross CA, Strynadka NC, Brown ED. Myers CL, et al. Among authors: french s. J Biol Chem. 2016 Dec 9;291(50):26066-26082. doi: 10.1074/jbc.M116.760447. Epub 2016 Oct 25. J Biol Chem. 2016. PMID: 27780866 Free PMC article.

10

The Genome-Wide Interaction Network of Nutrient Stress Genes in Escherichia coli.

Côté JP, French S, Gehrke SS, MacNair CR, Mangat CS, Bharat A, Brown ED. Côté JP, et al. Among authors: french s. mBio. 2016 Nov 22;7(6):e01714-16. doi: 10.1128/mBio.01714-16. mBio. 2016. PMID: 27879333 Free PMC article.

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