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Page 1
Exercise is associated with younger methylome and transcriptome profiles in human skeletal muscle.
Voisin S, Seale K, Jacques M, Landen S, Harvey NR, Haupt LM, Griffiths LR, Ashton KJ, Coffey VG, Thompson JM, Doering TM, Lindholm ME, Walsh C, Davison G, Irwin R, McBride C, Hansson O, Asplund O, Heikkinen AE, Piirilä P, Pietiläinen KH, Ollikainen M, Blocquiaux S, Thomis M, Coletta DK, Sharples AP, Eynon N. Voisin S, et al. Among authors: pietilainen kh. Aging Cell. 2024 Jan;23(1):e13859. doi: 10.1111/acel.13859. Epub 2023 May 2. Aging Cell. 2024. PMID: 37128843 Free PMC article.
Acquired obesity and poor physical fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity.
Mustelin L, Pietiläinen KH, Rissanen A, Sovijärvi AR, Piirilä P, Naukkarinen J, Peltonen L, Kaprio J, Yki-Järvinen H. Mustelin L, et al. Among authors: pietilainen kh. Am J Physiol Endocrinol Metab. 2008 Jul;295(1):E148-54. doi: 10.1152/ajpendo.00580.2007. Epub 2008 May 6. Am J Physiol Endocrinol Metab. 2008. PMID: 18460597 Free PMC article.
Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat.
Ollikainen M, Ismail K, Gervin K, Kyllönen A, Hakkarainen A, Lundbom J, Järvinen EA, Harris JR, Lundbom N, Rissanen A, Lyle R, Pietiläinen KH, Kaprio J. Ollikainen M, et al. Among authors: pietilainen kh. Clin Epigenetics. 2015 Apr 2;7(1):39. doi: 10.1186/s13148-015-0073-5. eCollection 2015. Clin Epigenetics. 2015. PMID: 25866590 Free PMC article.
Niacin Cures Systemic NAD+ Deficiency and Improves Muscle Performance in Adult-Onset Mitochondrial Myopathy.
Pirinen E, Auranen M, Khan NA, Brilhante V, Urho N, Pessia A, Hakkarainen A, Kuula J, Heinonen U, Schmidt MS, Haimilahti K, Piirilä P, Lundbom N, Taskinen MR, Brenner C, Velagapudi V, Pietiläinen KH, Suomalainen A. Pirinen E, et al. Among authors: pietilainen kh. Cell Metab. 2020 Jun 2;31(6):1078-1090.e5. doi: 10.1016/j.cmet.2020.04.008. Epub 2020 May 7. Cell Metab. 2020. PMID: 32386566 Free article.
Blood and skeletal muscle ageing determined by epigenetic clocks and their associations with physical activity and functioning.
Sillanpää E, Heikkinen A, Kankaanpää A, Paavilainen A, Kujala UM, Tammelin TH, Kovanen V, Sipilä S, Pietiläinen KH, Kaprio J, Ollikainen M, Laakkonen EK. Sillanpää E, et al. Among authors: pietilainen kh. Clin Epigenetics. 2021 May 17;13(1):110. doi: 10.1186/s13148-021-01094-6. Clin Epigenetics. 2021. PMID: 34001218 Free PMC article.
Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study.
Lapatto HAK, Kuusela M, Heikkinen A, Muniandy M, van der Kolk BW, Gopalakrishnan S, Pöllänen N, Sandvik M, Schmidt MS, Heinonen S, Saari S, Kuula J, Hakkarainen A, Tampio J, Saarinen T, Taskinen MR, Lundbom N, Groop PH, Tiirola M, Katajisto P, Lehtonen M, Brenner C, Kaprio J, Pekkala S, Ollikainen M, Pietiläinen KH, Pirinen E. Lapatto HAK, et al. Among authors: pietilainen kh. Sci Adv. 2023 Jan 13;9(2):eadd5163. doi: 10.1126/sciadv.add5163. Epub 2023 Jan 13. Sci Adv. 2023. PMID: 36638183 Free PMC article.
247 results