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Page 1
Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas.
Hariharan S, Whitfield BT, Pirozzi CJ, Waitkus MS, Brown MC, Bowie ML, Irvin DM, Roso K, Fuller R, Hostettler J, Dharmaiah S, Gibson EA, Briley A, Mangoli A, Fraley C, Shobande M, Stevenson K, Zhang G, Malgulwar PB, Roberts H, Roskoski M, Spasojevic I, Keir ST, He Y, Castro MG, Huse JT, Ashley DM. Hariharan S, et al. Among authors: bowie ml. bioRxiv [Preprint]. 2023 Apr 21:2023.04.20.537594. doi: 10.1101/2023.04.20.537594. bioRxiv. 2023. Update in: Nat Commun. 2024 Jan 25;15(1):730. doi: 10.1038/s41467-024-44932-w PMID: 37131619 Free PMC article. Updated. Preprint.
Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas.
Hariharan S, Whitfield BT, Pirozzi CJ, Waitkus MS, Brown MC, Bowie ML, Irvin DM, Roso K, Fuller R, Hostettler J, Dharmaiah S, Gibson EA, Briley A, Mangoli A, Fraley C, Shobande M, Stevenson K, Zhang G, Malgulwar PB, Roberts H, Roskoski M, Spasojevic I, Keir ST, He Y, Castro MG, Huse JT, Ashley DM. Hariharan S, et al. Among authors: bowie ml. Nat Commun. 2024 Jan 25;15(1):730. doi: 10.1038/s41467-024-44932-w. Nat Commun. 2024. PMID: 38272925 Free PMC article.
STING agonist 8803 reprograms the immune microenvironment and increases survival in preclinical models of glioblastoma.
Najem H, Lea ST, Tripathi S, Hurley L, Chen CH, William I, Sooreshjani M, Bowie M, Hartley G, Dussold C, Pacheco S, Dmello C, Lee-Chang C, McCortney K, Steffens A, Walshon J, Ott M, Wei J, Marisetty A, Balyasnikova I, Stupp R, Lukas RV, Hu J, James CD, Horbinski CM, Lesniak MS, Ashley DM, Priebe W, Platanias LC, Curran MA, Heimberger AB. Najem H, et al. J Clin Invest. 2024 Jun 17;134(12):e175033. doi: 10.1172/JCI175033. J Clin Invest. 2024. PMID: 38941297 Free PMC article.
Epigenetic STING silencing is developmentally conserved in gliomas and can be rescued by methyltransferase inhibition.
Low JT, Chandramohan V, Bowie ML, Brown MC, Waitkus MS, Briley A, Stevenson K, Fuller R, Reitman ZJ, Muscat AM, Hariharan S, Hostettler J, Danehower S, Baker A, Khasraw M, Wong NC, Gregory S, Nair SK, Heimberger A, Gromeier M, Bigner DD, Ashley DM. Low JT, et al. Among authors: bowie ml. Cancer Cell. 2022 May 9;40(5):439-440. doi: 10.1016/j.ccell.2022.04.009. Epub 2022 Apr 28. Cancer Cell. 2022. PMID: 35487217 Free article. No abstract available.
Evidence for phenotypic plasticity in aggressive triple-negative breast cancer: human biology is recapitulated by a novel model system.
D'Amato NC, Ostrander JH, Bowie ML, Sistrunk C, Borowsky A, Cardiff RD, Bell K, Young LJ, Simin K, Bachelder RE, Delrow J, Dawson A, Yee LD, Mrózek K, Clay TM, Osada T, Seewaldt VL. D'Amato NC, et al. Among authors: bowie ml. PLoS One. 2012;7(9):e45684. doi: 10.1371/journal.pone.0045684. Epub 2012 Sep 25. PLoS One. 2012. PMID: 23049838 Free PMC article.
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