McReynolds CB - Search Results

1

Randomized, double-blind, phase 1a single-ascending dose and food effect studies assessing safety and pharmacokinetics of EC5026 in healthy volunteers.

Schmidt WK, Cortés-Puch I, McReynolds CB, Croston GE, Hwang SH, Yang J, Pedersen TL, Wagner KM, Pham TT, Hunt T, Hammock BD. Schmidt WK, et al. Among authors: mcreynolds cb. Clin Transl Sci. 2024 Sep;17(9):e70033. doi: 10.1111/cts.70033. Clin Transl Sci. 2024. PMID: 39300734 Free PMC article. Clinical Trial.

2

Preclinical Evaluation of Soluble Epoxide Hydrolase Inhibitor AMHDU against Neuropathic Pain.

Babkov D, Eliseeva N, Adzhienko K, Bagmetova V, Danilov D, McReynolds CB, Morisseau C, Hammock BD, Burmistrov V. Babkov D, et al. Among authors: mcreynolds cb. Int J Mol Sci. 2024 Aug 14;25(16):8841. doi: 10.3390/ijms25168841. Int J Mol Sci. 2024. PMID: 39201526 Free PMC article.

3

Milestones Next Steps: Results of a Feedback Questionnaire.

McReynolds CB, Haynes I, McLean S, Edgar L. McReynolds CB, et al. J Grad Med Educ. 2023 Apr;15(2):268-271. doi: 10.4300/JGME-D-23-00113.1. Epub 2023 Apr 17. J Grad Med Educ. 2023. PMID: 37139215 Free PMC article. No abstract available.

4

The soluble epoxide hydrolase inhibitor TPPU improves comorbidity of chronic pain and depression via the AHR and TSPO signaling.

Luo A, Wu Z, Li S, McReynolds CB, Wang D, Liu H, Huang C, He T, Zhang X, Wang Y, Liu C, Hammock BD, Hashimoto K, Yang C. Luo A, et al. Among authors: mcreynolds cb. J Transl Med. 2023 Feb 2;21(1):71. doi: 10.1186/s12967-023-03917-x. J Transl Med. 2023. PMID: 36732752 Free PMC article.

5

Improved ELISA for linoleate-derived diols in human plasma utilizing a polyHRP-based secondary tracer.

Singh N, Li D, McReynolds CB, Morisseau C, Hammock BD. Singh N, et al. Among authors: mcreynolds cb. Anal Methods. 2022 May 13;14(18):1810-1819. doi: 10.1039/d2ay00272h. Anal Methods. 2022. PMID: 35481804 Free PMC article.

6

sEH-derived metabolites of linoleic acid drive pathologic inflammation while impairing key innate immune cell function in burn injury.

Bergmann CB, McReynolds CB, Wan D, Singh N, Goetzman H, Caldwell CC, Supp DM, Hammock BD. Bergmann CB, et al. Among authors: mcreynolds cb. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2120691119. doi: 10.1073/pnas.2120691119. Epub 2022 Mar 21. Proc Natl Acad Sci U S A. 2022. PMID: 35312372 Free PMC article.

7

Species Differences in Metabolism of Soluble Epoxide Hydrolase Inhibitor, EC1728, Highlight the Importance of Clinically Relevant Screening Mechanisms in Drug Development.

McReynolds CB, Yang J, Guedes A, Morisseau C, Garcia R, Knych H, Tearney C, Hamamoto B, Hwang SH, Wagner K, Hammock BD. McReynolds CB, et al. Molecules. 2021 Aug 19;26(16):5034. doi: 10.3390/molecules26165034. Molecules. 2021. PMID: 34443621 Free PMC article.

8

Plasma Linoleate Diols Are Potential Biomarkers for Severe COVID-19 Infections.

McReynolds CB, Cortes-Puch I, Ravindran R, Khan IH, Hammock BG, Shih PB, Hammock BD, Yang J. McReynolds CB, et al. Front Physiol. 2021 Apr 1;12:663869. doi: 10.3389/fphys.2021.663869. eCollection 2021. Front Physiol. 2021. PMID: 33868029 Free PMC article.

9

Movement to the Clinic of Soluble Epoxide Hydrolase Inhibitor EC5026 as an Analgesic for Neuropathic Pain and for Use as a Nonaddictive Opioid Alternative.

Hammock BD, McReynolds CB, Wagner K, Buckpitt A, Cortes-Puch I, Croston G, Lee KSS, Yang J, Schmidt WK, Hwang SH. Hammock BD, et al. Among authors: mcreynolds cb. J Med Chem. 2021 Feb 25;64(4):1856-1872. doi: 10.1021/acs.jmedchem.0c01886. Epub 2021 Feb 7. J Med Chem. 2021. PMID: 33550801 Free PMC article.

10

Soluble Epoxide Hydrolase Regulation of Lipid Mediators Limits Pain.

Wagner KM, Gomes A, McReynolds CB, Hammock BD. Wagner KM, et al. Among authors: mcreynolds cb. Neurotherapeutics. 2020 Jul;17(3):900-916. doi: 10.1007/s13311-020-00916-4. Neurotherapeutics. 2020. PMID: 32875445 Free PMC article. Review.

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